American Journal of Bioethics.

CRISPR Critters and CRISPR Cracks

This essay focuses on possible nonhuman applications of CRISPR/Cas9 that are likely to be widely overlooked because they are unexpected and, in some cases, perhaps even “frivolous.” We look at five uses for “CRISPR Critters”: wild de-extinction, domestic de-extinction, personal whim, art, and novel forms of disease prevention. We then discuss the current regulatory framework and its possible limitations in those contexts. We end with questions about some deeper issues raised by the increased human control over life on earth offered by genome editing.

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Volume 15, Issue 12
December 2015

Target Articles.

“Editing” Genes: A Case Study About How Language Matters in Bioethics Meaghan O'Keefe, Sarah Perrault, Jodi Halpern, Lisa Ikemoto, Mark Yarborough & UC North Bioethics Collaboratory for Life & Health Sciences
CRISPR Critters and CRISPR Cracks R. Alta Charo & Henry T. Greely
Human Germline CRISPR-Cas Modification: Toward a Regulatory Framework Niklaus H. Evitt, Shamik Mascharak & Russ B. Altman