Pediatric research without the potential for clinical benefit is vital to improving pediatric medical care. This research also raises ethical concern and is regarded by courts and commentators as unethical. While at least 10 justifications have been proposed in response, all have fundamental limitations. This article describes and defends a new justification based on the fact that enrollment in clinical research offers children the opportunity to contribute to a valuable project. Contributing as children to valuable projects can benefit individuals in two ways. First, individuals may come to ?embrace? the contributions they made as children. Second, contributing to valuable projects can lead to a better overall life. Because these potential benefits can outweigh small research risks, they provide a justification for pediatric research without the potential for clinical benefit, when it poses low risks and has the potential to benefit others in important ways.
Open Peer Commentaries.
- On Justifying Pediatric Research Without the Prospect of Clinical Benefit
- Why Even Inappropriate Parental Consent Might Be Enough to Justify Minimal Risk Pediatric Research Without Clinical Benefit
- Consent to Pediatric Research: A Couple of Distinctions
- The Concept of Clinical Research and its Ethical Relevance: The COMPAS Trial as a Case Study
- On Wendler's New Justification of Pediatric Research
- Justifying Pediatric Research Not Expected to Benefit Child Subjects
- A More Persuasive Justification for Pediatric Research