"The risks of trial participation for an individual are logically measured against what an individual’s care trajectory would have been had they pursued care outside of a trial. Randomization potentially abrogates that care trajectory."

https://t.co/VjyiFi99VL

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"Assuming that the specificity of the information has been confirmed, the resources and time required for researchers to disclose it to organizational decision makers should be modest."

Whicher & Wu's OPC, responding to Morain et al's TA on PCTs: https://t.co/3tx2OdSNgA

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"What are the attitudes of prospective patient-subjects? Do their preferences differ based upon the type of finding, such as whether it relates to prevention of a future health risk versus treatment of an existing condition?"

Qs and A's from Morain et al https://t.co/o9BDj4MgK5