|
|
Propranolol and the Prevention of Post-Traumatic Stress Disorder: Is it Wrong to Erase the 'Sting' of Bad Memories?
by Michael Henry, Jennifer R. Fishman, Stuart J. Youngner 2007. The American Journal of Bioethics 7(9):12
Abstract/Extract The National Institute of Mental Health (Bethesda, MD) reports that
approximately 5.2 million Americans experience post-traumatic stress
disorder (PTSD) each year. PTSD can be severely debilitating and
diminish quality of life for patients and those who care for them.
Studies have indicated that propranolol, a beta-blocker, reduces
consolidation of emotional memory. When administered immediately after
a psychic trauma, it is efficacious as a prophylactic for PTSD. Use of
such memory-altering drugs raises important ethical concerns, including
some futuristic dystopias put forth by the President's Council on
Bioethics. We think that adequate informed consent should facilitate
ethical research using propranolol and, if it proves efficacious,
routine treatment. Clinical evidence from studies should certainly
continue to evaluate realistic concerns about possible ill effects of
diminishing memory. If memory-attenuating drugs prove effective, we
believe that the most immediate social concern is the
over-medicalization of bad memories, and its subsequent exploitation by
the pharmaceutical industry.
|
|