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EDITORIAL

Vaccine Mandates Are Justifiable Because We Are All in This Together
John D. Lantos and Mary Anne Jackson

Influenza is a deadly disease. Every year, in the United States, 200,000 people are hospitalized with influenza and 23,000–33,000 people die of the disease (Heron 2008). Unimmunized health care workers are at high risk for exposure and subsequent infection and may spread disease to hospitalized patients (Elder et al. 1996). Given these facts, most public health authorities, infectious disease ...

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Target Article

Ethics of Clinical Science in a Public Health Emergency: Drug Discovery at the Bedside
Sarah J. L. Edwards

Clinical research under the usual regulatory constraints may be difficult or even impossible in a public health emergency. Regulators must seek to strike a good balance in granting as wide therapeutic access to new drugs as possible at the same time as gathering sound evidence of safety and effectiveness. To inform current policy, I reexamine the philosophical rationale for restricting new medicin...

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An Ethical Analysis of Mandatory Influenza Vaccination of Health Care Personnel: Implementing Fairly and Balancing Benefits and Burdens
Armand H. Matheny Antommaria

Health care institutions have paid increasing attention to preventing nosocomial transmission of influenza through vaccination of health care personnel. While multifaceted voluntary interventions have increased vaccination rates, proponents of mandatory programs contend the rates remain unacceptably low. Conventional bioethical analyses of mandatory programs are inadequate; they fail to account fo...

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