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Opioid Abuse May Be Curbed by New Vaccine

External Link - Source: Genetic Engineering and Biotechnology News

In preclinical studies, a vaccine has been shown to induce antibodies that bind to heroin and keep it from crossing the blood–brain barrier. The vaccine, a haptenic heroin surrogate, was conjugated to tetanus toxoid and mixed with liposomes containing monophosphoryl lipid A as an adjuvant. It reduced heroin-induced antinociception and locomotive behavioral changes following repeated subcutaneous and intravenous heroin challenges in mice and rats.

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