The Food and Drug Administration on Friday cleared the first treatment for patients with advanced breast cancer caused by BRCA mutations, which are genetic defects that raise the risk of malignancies.
The New England Journal of Medicine
As clinicians in the United States prepare for the start of another influenza season, experts have been watching the Southern Hemisphere winter for hints of what might be in store for us in the North. Reports from Australia have caused mounting concern, with record-high numbers of laboratory-confirmed influenza notifications and outbreaks and higher-than-average numbers of hospitalizations and deaths.
A Cleveland Clinic surgeon accused of sexually assaulting two patients was kept on staff at the prominent Ohio hospital during confidential settlement negotiations
With a tell-all book raising concerns about US President Trump’s mental stability, there is a renewed question asking why the most powerful man in the world is not required to pass a thorough mental health exam.
The suggestion that women are not advancing in science because of innate inability is being taken seriously by some high-profile academics.
For the first time, scientists have produced evidence in living humans that the protein tau, which mars the brain in Alzheimer’s disease, spreads from neuron to neuron. Although such movement wasn’t directly observed, the finding may illuminate how neurodegeneration occurs in the devastating illness, and it could provide new ideas for stemming the brain damage that robs so many of memory and cognition.
Washington state residents who don’t identify as male or female will soon be able to choose X as their gender on birth certificates.
Technique to knock out mutant gene relies on fatty molecules to deliver CRISPR components to inner-ear cells.
Efforts to control dengue suffered a major setback in late November when Sanofi Pasteur announced that its vaccine, the only one on the market, should only be given to those who have already had one infection with the mosquito-borne disease that affects millions of people in the tropics each year.
The tumor is benign but, if left untreated, it will kill Emanuel. As it grows, it is slowly suffocating the teen.
The Mayo Clinic is building its future around high-tech approaches to research known as “precision medicine.” This involves gathering huge amounts of information from genetic tests, medical records and other data sources to ferret out unexpected ideas to advance health. But one longtime scientist at the Mayo Clinic isn’t playing along. Dr. Michael Joyner is a skeptical voice in a sea of eager advocates.
A Pennsylvania doctor charged with causing the deaths of five patients by unlawfully prescribing opioids surrendered his license to prescribe controlled substances at a federal court hearing.
Journal Of Medical Ethics
Dr. Mehmet Oz is widely known not just as a successful media personality donning the title “America’s Doctor,” but, we suggest, also as a physician visibly out of step with his profession. A recent, unsuccessful attempt to censure Dr. Oz raises the issue of whether the medical profession can effectively self-regulate at all. It also raises concern that the medical profession’s self-regulation might be selectively activated, perhaps only when the subject of professional censure has achieved a level of public visibility.
These base makeovers are setting the scene for the launch of Holistic Health and Fitness (H2F), a larger initiative — a decade in the making and still pending final approval — that strives to radically change how the Army prepares service members. The proposal includes the introduction of a new field manual for training, plus the creation of Soldier Performance Readiness Centers (SPRC, pronounced “spark”), which will be state-of-the-art fitness facilities staffed by experts who can educate and offer real-time feedback on proper form, psychological well-being, nutrition and more.
Scientists could soon resume controversial experiments on germs with the potential to cause pandemics, as government officials have decided to finally lift an unusual three-year moratorium on federal funding for the work. The research involves three viruses — influenza, SARS, and MERS — that could kill millions if they mutated in a way that let the germs spread quickly among people.
The family that spits together might not want to receive their health results together. In the new era of DNA testing, there can be tricky family dynamics.
The bill prohibits abortions after tests reveal Down syndrome in a fetus or if there’s “any other reason to believe” the fetus has the genetic condition. A person performing an abortion in such a case could face a fourth-degree felony charge, and physicians could lose their licenses. The woman seeking the abortion would not be held accountable, according to the bill.
Simon Bramhall, 53, pleaded guilty Wednesday to two counts of assault by beating after he burned his initials into two of his patients’ organs in 2013.
Genetic Engineering and Biotechnology News
In preclinical studies, a vaccine has been shown to induce antibodies that bind to heroin and keep it from crossing the blood–brain barrier. The vaccine, a haptenic heroin surrogate, was conjugated to tetanus toxoid and mixed with liposomes containing monophosphoryl lipid A as an adjuvant. It reduced heroin-induced antinociception and locomotive behavioral changes following repeated subcutaneous and intravenous heroin challenges in mice and rats.
The U.S. research community experienced both the thrill of victory and the agony of defeat in lobbying congressional Republicans as they wrapped up a major overhaul of the nation’s tax code.
Authorities in the Chinese province of Xinjiang have begun collecting DNA and biometrics from all its residents, Human Rights Watch reported Wednesday.
The Delhi government has canceled the license of a private hospital where a newborn baby was mistakenly declared dead.
Konduros, 53, who runs a bakery and cafe in southeastern Ontario, is one of 10 men in an early-stage trial sponsored by Spark Therapeutics. (The disorder is much more common in men than women.) On Wednesday, researchers reported that a single intravenous infusion of Spark’s novel gene therapy enabled patients to safely produce sufficient clotting factor to prevent dangerous bleeding episodes.
Scientists once had high hopes that inhibiting a hormone named ghrelin would be the key to preventing obesity. Ghrelin didn’t turn out to be a weight loss panacea. But now, the discovery of the first molecule naturally made by the body that blocks ghrelin’s effects may open up new avenues for treating other conditions, including diabetes and anorexia. The finding may also explain some of the benefits of bariatric surgery, which shrinks or reroutes the stomach to control weight.
Government of Canada
Without access to detailed clinical data, health professionals and researchers are unable to perform independent analyses of the evidence underlying published research findings and Health Canada’s regulatory reviews. This approach limits transparency and misses opportunities to promote greater confidence in the oversight of drugs and medical devices. It is also out of step with Health Canada’s key regulatory partners, including the European Medicines Agency (EMA) and the U.S. Food and Drug Administration, which have increased clinical data transparency over the past 10 years.
People rely on organ donations to save their lives, but a California woman claims that her implanted pancreas gave her cancer, reported Courthouse News. The legal news service found court documents of the complaint, which was filed in the Sacramento Superior Court. Jeffrey Sevey, attorney for the plaintiff, confirmed to Newsweek that put in the paperwork.
Scientists fear plans to abandon clinical trials of centuries-old remedies will put people at risk.