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03/07/2017

Climate change threatens to wash away couple’s history

CNN

Seventy years ago, on the day Wenceslaus and Denicia Billiot got married, their wedding party danced along a road that ran from one end of Isle de Jean Charles to the other.

Today, that road is nearly gone. Isle de Jean Charles, located 80 miles from New Orleans, has been sinking slowly. Since 1955, it has lost 98% of its land mass to rising sea levels, devastating hurricanes, and the construction of oil and gas canals along the marsh.

03/06/2017

Polluted environments kill 1.7 million children each year, WHO says

CNN

Each year, environmental pollutants cost an estimated 1.7 million lives among children under 5, according to World Health Organization reports released Monday.

03/03/2017

A divided White House still offers little guidance on replacing Obamacare

Washington Post

A meeting Friday afternoon between President Trump and Ohio Gov. John Kasich, his former rival in the GOP primaries, had no set agenda. But Kasich came armed with one anyway: his hope to blunt drastic changes to the nation’s health-care system envisioned by some conservatives in Washington.

03/02/2017

An epigenetics gold rush: new controls for gene expression

Nature

Over the past few years, researchers have identified some of the machinery involved in regulating these marks. Each requires a writer to place it, an eraser to remove it and a reader to interpret it. As the identities of these proteins emerged, scientists have come to understand that m6A affects not only RNA splicing, but also translation and RNA stability.

03/01/2017

Ebola funding surge hides falling investment in other neglected diseases

Nature

Global funding for research on neglected diseases — which include tuberculosis, HIV/AIDS and malaria — is at its lowest level since 2007, according to the annual G-FINDER investment report by Policy Cures Research, a health-policy analysis firm in Sydney, Australia.

02/28/2017

Biologists propose to sequence the DNA of all life on Earth

Science

Yesterday, at a meeting here organized by the Smithsonian Initiative on Biodiversity Genomics and the Shenzhen, China–based sequencing powerhouse BGI, a small group of researchers upped the ante even more, announcing their intent to, eventually, sequence “all life on Earth.”

02/27/2017

U.S. researchers guilty of misconduct later won more than $100 million in NIH grants, study finds

Science

Overall, 23 of the scientists (roughly 8% of sanctioned researchers) received NIH funding after receiving an ORI sanction. Of that group, 17 researchers won more than $101 million for 61 new projects. Thirteen continued to receive funding from NIH grants that had been awarded before being sanctioned.

02/24/2017

The Birth of CRISPR Inc

Science

As the science grew even more compelling and venture capital (VC) beckoned, the jockeying to start CRISPR companies became intense. The research community was rent apart by concerns about intellectual property, academic credit, Nobel Prize dreams, geography, media coverage, egos, personal profit, and loyalty. A billion dollars poured into what might be called CRISPR Inc.

02/23/2017

How Silicon Valley Is Trying to Hack Its Way Into a Longer Life

Time

Rather than wait years for treatments to be approved by federal officials, many of them are testing ways to modify human biology that fall somewhere on the spectrum between science and entrepreneurialism. It’s called biohacking, and it’s one of the biggest things happening in the Bay Area.

02/22/2017

Artificial intelligence grows a nose

Science

Now, 22 teams of computer scientists have unveiled a set of algorithms able to predict the odor of different molecules based on their chemical structure. It remains to be seen how broadly useful such programs will be, but one hope is that such algorithms may help fragrancemakers and food producers design new odorants with precisely tailored scents.

02/21/2017

Harvard and M.I.T. Scientists Win Gene-Editing Patent Fight

The New York Times

The Broad Institute in Cambridge, Mass., will retain potentially lucrative rights to a powerful gene-editing technique that could lead to major advances in medicine and agriculture, the federal Patent and Trademark Office ruled on Wednesday.

02/17/2017

An old drug gets a new price to fight a rare disease: $89,000 a year

Washington Post

An old steroid treatment, long available outside the United States, received approval this week for a rare disease that afflicts about 15,000 Americans. Though not previously approved in the United States, the drug, deflazacort, has for years been available to patients suffering from the devastating and fatal disease Duchenne muscular dystrophy; families can import it from abroad for about $1,200 per year on average. The new list price for the drug? $89,000 a year.

02/16/2017

Speedy drug approvals are risky, but drug companies have another idea that’s just terrible

Los Angeles Times

As with Trump’s proposed elimination of consumer safeguards, environmental-protection measures and financial reforms, the reality is that if his administration proceeds with a wholesale deregulation of the drug industry, the public will be largely undefended against the aggressive and potentially dangerous predations of multibillion-dollar conglomerates.

02/15/2017

This stereotype is killing black children

Washington Post

USA Swimming, the nation’s organizing body for the sport, has some 337,000 members — of whom only 1.3 percent are black. Today, nearly 60 years after the abolishment of Jim Crow laws that kept African Americans from pools and safe swimming places, many children still never get the chance to swim.

02/14/2017

French auditors criticize €5-billion science super-campus near Paris

Nature

France’s government auditor has taken a sharp swipe at efforts to develop a science super-campus near Paris that, by 2020, was supposed to rival the world’s top campus universities, such as the US Massachusetts Institute of Technology (MIT). More than €5.3 billion (US$5.7 billion) in public spending has been earmarked for the Paris-Saclay science cluster, the Court of Auditors estimates in an annual report published on 8 February — but the original vision of creating a large integrated research university there is “at a standstill”.

02/13/2017

Senate confirms Price to lead HHS

Science

Price now takes the helm of a $1 trillion government department that includes the National Institutes of Health (NIH), the Centers for Disease Control and Prevention, and the Food and Drug Administration (FDA). Most visibly, he will be charged with overseeing the repeal and replacement of the Affordable Care Act, also known as Obamacare, that Republicans have promised.

02/10/2017

Brain researchers fight National Hockey League’s demand for records

Science

A pair of Boston University (BU) brain researchers is pushing back against demands by the National Hockey League (NHL) that they release data, brain pathology slides, and interview records of former NHL players and their families. The scientists accumulated the records during their research on chronic traumatic encephalopathy (CTE), a neurodegenerative disease that has been linked to repetitive head trauma.

02/09/2017

India scraps funding ties with Gates Foundation on immunization

Reuters

A group backed by the Bill & Melinda Gates Foundation that works on India’s immunization program will now be funded by the health ministry, a government official said, a move in part prompted by fears foreign donors could influence policy making.

02/08/2017

Hawaii seeks to ban ‘reef-unfriendly’ sunscreen

Nature

Legislators in Hawaii are trying to ban the sale of sunscreens that contain two UV-filtering chemicals, after studies suggested that they harm coral reefs.

02/07/2017

USDA blacks out animal welfare information

Science

The U.S. Department of Agriculture (USDA) today removed public access to tens of thousands of reports that document the numbers of animals kept by research labs, companies, zoos, circuses, and animal transporters—and whether those animals are being treated humanely under the Animal Welfare Act. Henceforth, those wanting access to the information will need to file a Freedom of Information Act request.

02/06/2017

Will the Trump presidency mean the end of FDA drug regulation?

Los Angeles Times

Donald Trump will be coming into office waving the banner of deregulation. While most of the speculation about his plans has focused on the financial industry and the possibility of eviscerating Dodd-Frank reforms, keep your eyes on the Food and Drug Administration. In a Trump administration the agency, figuratively speaking, will have a big bull’s-eye on its back.

02/03/2017

On 22 April, empiricists around the country will march for science

Science

Some fear a demonstration led by researchers might only serve to paint scientists as an interest group, further politicizing scientific issues. And at least one veteran science lobbyist has urged organizers to make sure it’s a march for science, not scientists.

02/02/2017

Gene drives thwarted by emergence of resistant organisms

Nature

By studying the insects under more-natural conditions, scientists hope to better understand how to eradicate them — and malaria — using an emerging genetic-engineering technology called gene drives. The technique can quickly disseminate genetic modifications in wild populations through an organism’s offspring, prompting some activists to call for it to be shelved. Yet gene drives might not be as effective as activists think. Recent research has identified a major hurdle to using them to eliminate diseases and vanquish invasive pests: evolution.

02/01/2017

Meet the scientists affected by Trump’s immigration ban

Science

Kaveh Daneshvar was thrilled when he was invited to speak at a molecular biology meeting next month in Banff, Canada. Daneshvar, a molecular geneticist, is finishing a postdoc at Harvard Medical School and Massachusetts General Hospital in Boston and preparing to go on the job market. He hoped that the conference talk would give him much-needed exposure to leaders in his field.

01/31/2017

Vaccine initiative marks bold resolution

Science

Clearly, private companies cannot be expected to invest on their own. But it is incumbent on governments to invest, and thus address this market failure, in partnership with pharma. It is therefore encouraging that there is now a solid plan to do just that: the Coalition for Epidemic Preparedness Innovations (CEPI), launched on 18 January at the World Economic Forum in Davos, Switzerland, aims to develop and take through early clinical trials vaccines against potential threats. It already has enough cash to work on three — MERS, Nipah-virus infection and Lassa fever.

01/30/2017

Journals invite too few women to referee

Nature

Using a large data set that includes the genders and ages of authors and reviewers from 2012 to 2015 for the journals of the American Geophysical Union (AGU), we show that women were used less as reviewers than expected (on the basis of their proportion of membership of the society and as published authors in AGU journals). The bias is a result of authors and editors, especially male ones, suggesting women as reviewers less often, and a slightly higher decline rate among women in each age group when asked.

01/27/2017

Japanese military entices academics to break taboo

Science

In 1950, Japan’s scientific community, chastened by the complicity of researchers in their nation’s disastrous military adventurism, took an extraordinary vow. “To preserve our integrity as scientists, we express our firm commitment both domestically and abroad that we will never pursue scientific research for the purpose of war,” declared the Science Council of Japan (SCJ), now the nation’s equivalent to the U.S. National Academies of Sciences, Engineering, and Medicine.

01/26/2017

Human tissues in a dish: The research and ethical implications of organoid technology

Science

Growing functional human tissues and organs would provide much needed material for regeneration and repair. New technologies are taking us in that direction. In addition to their use in regenerative medicine, stem cells that grow and morph into organ-like structures known as organoids can be used in drug development and toxicology testing. The potential developments and possibilities are numerous and affect not only biomedicine but also areas of ongoing ethical debate.

01/25/2017

We spoke with the man who could lead the world’s top health organization

Business Insider

The WHO lost a lot of trust in the aftermath of the 2014 Ebola outbreak in West Africa. Nabarro said his hope is to make sure that doesn’t happen again.

01/24/2017

With executive order, Trump tosses a ‘bomb’ into fragile health insurance markets

Washington Post

The practical implications of Trump’s action on Friday are harder to decipher. Its language instructs all federal agencies to “waive, defer, grant ­exemptions from or delay” any part of the law that imposes a financial or regulatory burden on those affected by it. That would cover consumers, doctors, hospitals and other providers, as well as insurers and drug companies.