Tag: enhancement

Blog Posts (65)

February 4, 2016

The next round of conversations about gene editing

This blog has carried several posts about the ethical issues surrounding gene editing in humans.  The next round of public discussions is scheduled for next week, Feb. 11-12. The National Academies of Science and Medicine have been holding meetings to address the state of the science and the attendant ethical issues.  In December, a first meeting was held in Washington, DC.  That meeting produced a... // Read More »
January 7, 2016

A Book for Anyone Interested in Bioethics

Being Human: Core Readings in the Humanities, edited by Leon Kass, is one book worth a spot on the shelf of anyone interested in bioethics or concerns about human dignity.  A series of excerpts from things that we read—or should have read—in high school or college, it was selected by the members of President George W. Bush’s President’s Council on Bioethics in 2003.  The readings... // Read More »
December 31, 2015

“Shrinking” IRBs and Cutting-Edge Bioethics

A recent conversation from my IRB work—for several reasons, I must limit the details of the case: An IRB had received, for review and approval, a research protocol for gene editing of human embryos obtained from an IVF clinic.  The embryos would be at about the 150-cell stage—an early stage at which some (incorrectly, as I understand the science) believe a fertilized, dividing-and-differentiating zygote has... // Read More »
December 4, 2015

Human Gene Editing: Half Speed Ahead?

A 3-day international conference on human gene editing has ended, with the conferees reportedly having issued a statement declaring it would be “irresponsible” to try to initiate a human pregnancy with an embryo that had some genes edited by modern techniques, much less create a human embryo using sperm or an egg that had been gene-edited.  In the latter case, the changes would be heritable,... // Read More »
September 25, 2015

A bit more about “3-parent babies”

It is reported that the UK’s Human Fertilisation and Embryology Authority (HFEA) issued guidelines last week to govern the practice of mitochondrial transfer, which the UK government approved in February.  In this case, the term “mitochondrial transfer” refers to any of several possible techniques that could be used to allow women with certain rare but debilitating diseases of the mitochondria—the “energy factories” of the cell—to... // Read More »
September 24, 2015

How Minimization Hurts Society

guest post by Christina Sisti Doctors and nurses are becoming more accustomed to those who are seeking a confirmation of their home diagnosis but how do they know when a patient isn’t telling them everything? Every day we put on our game face or our poker face which minimizes our emotions. Our poker faces are costing us our health. Minimization reduces the chances of a... // Read More »
July 31, 2015

On the Safety Argument Against Gene Editing

As discussed in an exchange earlier this year on this blog, one of the concerns about editing the human germline is that the risks to the next generation and future generations are not predictable, and the experiments to address those safety concerns cannot be done ethically.  Go here, and to the embedded links, to review.  Recently, Paige Cunningham and Michael Sleasman of the Center for... // Read More »
May 14, 2015

Still More on Gene Editing

Joe Gibes (May 9) and Steve Phillips (May 13) took up the challenge I posted last week: to address whether human germline gene editing, even in a hypothetically-narrow example case, is morally unacceptable in some intrinsic sense, and therefore something that ought never be attempted or, for that matter, pursued in the laboratory.  If you have not read their posts, please do so. To come... // Read More »
May 8, 2015

Gene Editing—Trying to Get Specific

In a comment last week, Mark McQuain pointed out the article “Engineering the Perfect Baby” in the MIT Technology Review.  Freely accessible online, it describes, in non-technical terms, several of the routes that genetic editing may follow.  Perhaps the most explosive:  adult skin cell transformed into an induced pleuripotent stem cell that then is used to give rise to germ cells that are then genetically... // Read More »
April 30, 2015

More on Gene Editing

The recently-public discussion of gene editing has been going on for over a month now.  I have been meaning to try to catch up with some of it.  Tuesday’s post by Courtney Thiele got there first.  This post will attempt to amplify a bit on what Courtney wrote. As Courtney pointed out, the technology involves making selective genetic changes of interest, including, but clearly not... // Read More »