Tag: reproduction

Blog Posts (103)

February 17, 2017

Human germline gene editing full report—a bit more

As Steve Phillips pointed out yesterday, the National Academies of Science, Engineering, and Medicine has published, in book form, its full report on “Human Gene Editing: Science, Ethics, and Governance.”  On Valentine’s day.  (I suppose it’s not so ironic.)  The entire report may be downloaded for free through this link.  Also available at that page are links to a 4-page summary report and to one-pagers... // Read More »
February 15, 2017

Is there a compelling reason for germline genetic editing?

Yesterday the National Academy of Sciences and the National Academy of Medicine release the findings of an expert panel on Human Genome Editing. The most significant of their recommendations relate to human germline genetic editing. They recognize that the techniques for doing this are not yet at the point that they can be considered safe enough to do at the present, but make the assumption... // Read More »
January 22, 2017

The Semantics of Therapy

What is therapy? This is one question that should occur to the reader of Jill Neimark’s “Unexpected Risks Found In Replacing DNA To Prevent Inherited Disorders.” In referring to the birth of the baby born of three parents last year, the author names it “mitochondrial replacement therapy”: Using a technique called mitochondrial replacement therapy, the researchers combined DNA from two women and one man to bypass... // Read More »
December 14, 2016

Pushing the IVF ethical envelop

When we discuss IVF in the Medical Ethics class that I teach we talk about the concern that IVF opens up the possibility of doing things that are at best morally questionable. There are also concerns that IVF fundamentally alters how children are created and should not be done under any circumstances, but many of my students are not ready to go that far. They... // Read More »
December 11, 2016

The 14-day rule: Time to double down?

The “world’s leading scientists” gathered at University College London on 7 December 2016 to explore extending the 14-day limit on embryo experimentation from 14 days to 28 days. Presently the consensus of that meeting is not known. The Guardian has published a nice summary of the background and future implications of the issue (link HERE). Jon Holmlund offered his comments in this blog back in... // Read More »
December 1, 2016

“3-Parent Babies” Sally Forth

The journal Nature reports that scientists advising the U.K.’s Human Fertilization and Embryology Authority (HEFA) have judged that attempts to bring so-called “3-parent babies” to birth is “ready for limited clinical testing.”   Presumably this means that the underlying technology, mitochondrial replacement, has been tested enough in the laboratory that it’s ready to try for human procreation.  Also presumably, HEFA will promulgate rules or guidelines to... // Read More »
October 22, 2016

Another Ethical Slippery Slope for A.R.T.?

Medical business opportunities usually seem to make for interesting ethical discussions these days. Forbes recently published an article showcasing Prelude Fertility, an assisted reproduction technology (ART) start-up seeking to combine all the technologies of egg harvesting, cryopreservation and IVF under one umbrella for the purpose of controlling one’s biological clock. Aside from the business issues, the article does a fair job of discussing the medical... // Read More »
October 7, 2016

More on Gene Editing

One version of the headline of a news item in Nature this week is, “UK bioethicists eye designer babies and CRISPR cows.” The UK’s Nuffield Council on Bioethics has just released a report, “Genome editing: an ethical review.”  The full report and a short summary are available for download here. I must say that my understanding of recent bioethical reflection in the UK leads me... // Read More »
September 29, 2016

Does Mitochondrial Transfer Really Save Lives?

This blog has discussed Mitochondrial Transfer, also referred to as Mitochondrial Replacement Techniques (MRTs), several times in the past (HERE and HERE to link a few.). The reason for further comment is that Dr. John Zhang, a New York-based fertility specialist admitted that he assisted in the successful fertilization and healthy delivery of a now 5 month old baby boy using the technique of Mitochondrial... // Read More »
August 26, 2016

Public discussions on human gene editing

On August 3, the National Academies of Science, Engineering, and Medicine posted online the slides and talks from its July 12 meeting to discuss public implications of the Human Gene-Editing Initiative.  A total of four meetings plus a related workshop were held: an introductory discussion in December 2015, followed by three more substantial meetings plus the related workshop in February, April, and now July of... // Read More »