Tag: research ethics

Blog Posts (43)

June 15, 2015

Welcoming the Concept of Alief to Medical Ethics

Welcoming the Concept of Alief to Medical Ethics

 by J.S. Blumenthal-Barby, Ph.D.

Philosopher Tamar Gendler has introduced (circa 2008) a new concept in the philosophical literature that could be of interest to medical ethicists.…

April 19, 2013

John Lantos, MD weighs in on the SUPPORT study

David Magnus, Ph.D.

John Lantos, MD weighs in on the SUPPORT study. He points out that the work of self-appointed “watch-dogs” such as Public Citizen and the Alliance for Human Research Protection are a danger to bioethics.…

April 18, 2013

NEJM Responses to the support controversy

David Magnus, Ph.D.

The New England Journal of Medicine ‘s web site has the early publication of an editorial about the controversy over the SUPPORT study of oxygen saturation levels in premature infants.…

April 4, 2013

Check out the April 2013 issue of AJOB!



February 19, 2013

"Innovative Treatment" vs Research: Which Is It?

Maurice Bernstein, M.D.

When does a doctor’s treatment of a patient become medical or surgical research? If what the doctor does is a standard and accepted method of therapy using proven medications or surgical techniques and represents nothing novel then at first glance what is occurring cannot be designated as research or can it?

December 14, 2012

Operation Delirium

Craig M. Klugman, Ph.D.

Joining the long line of examples of concerning human subjects research experiments is a profile in The New Yorker (December 17).…

September 1, 2012

AJOB's September Issue is Here!

This month’s issue features:


February 10, 2012

Is Hope a Culprit in Cancer Clinical Trials?

A recent study conducted by Emory University School of Medicine found that therapeutic misconception is alive and well in Phase I cancer research.…

November 3, 2011

November Issue of AJOB is Now Available Online!

This month’s issue of The American Journal of Bioethics is now available online. Research ethics is featured prominently in this issue with Rosamond Rhodes et al arguing for a new category of research risk and an article about the recruitment of research participants.…

October 4, 2011

A Duty to Report Dead Ends?

When an investigational agent is being studied by pharma, is there an ethical responsibility to disclose the findings of that research, even if the agent is no longer being studied or being brought to market?…

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Published Articles (43)

American Journal of Bioethics: Volume 16 Issue 10 - Oct 2016

Healing Without Waging War: Beyond Military Metaphors in Medicine and HIV Cure Research Jing-Bao Nie, Adam Gilbertson, Malcolm de Roubaix, Ciara Staunton, Anton van Niekerk, Joseph D. Tucker & Stuart Rennie

American Journal of Bioethics: Volume 15 Issue 9 - Sep 2015

Patient Perspectives on the Learning Health System: The Importance of Trust and Shared Decision Making Maureen Kelley, Cyan James, Stephanie Alessi Kraft, Diane Korngiebel, Isabelle Wijangco, Emily Rosenthal, Steven Joffe, Mildred K. Cho, Benjamin Wilfond & Sandra Soo-Jin Lee

American Journal of Bioethics: Volume 15 Issue 9 - Sep 2015

Prudentia Populo: Involving the Community in Biobank Governance Megan A. Allyse, Jennifer B. McCormick & Richard R. Sharp

American Journal of Bioethics: Volume 15 Issue 4 - Apr 2015

Examining the Ethics of Clinical Use of Unproven Interventions Outside of Clinical Trials During the Ebola Epidemic Seema K. Shah, David Wendler & Marion Danis

American Journal of Bioethics: Volume 15 Issue 4 - Apr 2015

Selecting the Right Tool For the Job Arthur L. Caplan, Carolyn Plunkett & Bruce Levin

American Journal of Bioethics: Volume 15 Issue 3 - Mar 2015

The Social Determinants of Health: Why Should We Care? Adina Preda & Kristin Voigt

American Journal of Bioethics: Volume 14 Issue 12 - Dec 2014

Shared Vulnerabilities in Research Eric Chwang

American Journal of Bioethics: Volume 11 Issue 11 - Nov 2011

“You Don't Know Me, But …”: Access to Patient Data and Subject Recruitment in Human Subjects Research Toby Schonfeld, Joseph S. Brown, N. Jean Amoura & Bruce Gordon

American Journal of Bioethics: Volume 14 Issue 11 - Nov 2014

Ethical Justifications for Access to Unapproved Medical Interventions: An Argument for (Limited) Patient Obligations Mary Jean Walker, Wendy A. Rogers & Vikki Entwistle

American Journal of Bioethics: Volume 14 Issue 11 - Nov 2014

Compassion and Research in Compassionate Use David Magnus

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News (116)

October 4, 2016 8:00 am

Are Swedish Designer Babies Coming Soon? (Seeker)

A Swedish medical researcher has taken another step toward eventually being able to engineer a custom-made human being. The experiment, first reported on NPR Thursday involves editing the genes of a developing human embryo.

September 15, 2016 8:00 am

Stop ignoring misconduct (Nature)

The history of science shows that irreproducibility is not a product of our times. Some 350 years ago, the chemist Robert Boyle penned essays on “the unsuccessfulness of experiments”. He warned readers to be sceptical of reported work. “You will meet with several Observations and Experiments, which … may upon further tryal disappoint your expectation.” He attributed the problem to a ‘lack of skill in the scientist and the lack of purity of the ingredients’, and what would today be referred to as inadequate statistical power.

September 14, 2016 8:00 am

How the Sugar Industry Shifted Blame to Fat (NY Times)

The sugar industry paid scientists in the 1960s to play down the link between sugar and heart disease and promote saturated fat as the culprit instead, newly released historical documents show.

September 9, 2016 8:00 am

Another scathing report causes more eminent heads to roll in the Macchiarini scandal (Science)

The scandal surrounding Paolo Macchiarini, the former star surgeon who became famous for his pioneering trachea transplants, has prompted yet another round of resignations and firings at the highest levels of Swedish higher education. On Monday evening, Swedish Minister for Higher Education and Research Helene Hellmark Knutsson said she had dismissed the country’s chancellor in charge of all public universities, Harriet Wallberg-Henriksson, following the release of a sharply critical report by an independent commission that examined the Karolinska Institute’s (KI’s) hiring and management of Macchiarini. Wallberg-Henriksson was vice-chancellor of KI in Stockholm, a position comparable to that of a university president, when Macchiarini was hired, and played a key role in his recruitment.

September 9, 2016 8:00 am

Blue ribbon report urges U.S. cancer moonshot to invest in 10 promising areas (Science)

Vice President Joe Biden’s proposed moonshot to conquer cancer should invest in large collaborations, data sharing projects, and the promising cancer treatment known as immunotherapy, among 10 areas described in an advisory group’s draft report released this morning. The report was accepted (with one abstention) today by the National Cancer Institute’s (NCI’s) advisory board, which is expected to pass it on to the NCI director and then to a federal task force. Now, Congress just needs to come up with the money to pay for the moonshot, research advocates say.

August 9, 2016 8:00 am

Beyond CRISPR: A guide to the many other ways to edit a genome (Nature)

The CRISPR–Cas9 tool enables scientists to alter genomes practically at will. Hailed as dramatically easier, cheaper and more versatile than previous technologies, it has blazed through labs around the world, finding new applications in medicine and basic research.

August 8, 2016 11:58 am

NIH Plans To Lift Ban On Research Funds For Part-Human, Part-Animal Embryos (NPR)

The federal government announced plans Thursday to lift a moratorium on funding of certain controversial experiments that use human stem cells to create animal embryos that are partly human.

August 5, 2016 12:19 pm

Medical Studies Involving Children Often Go Unpublished (NPR)

Many medical studies involving children never end up being put to use because scientists frequently don’t publish the results of their work, according to an analysis published online Thursday.

August 3, 2016 8:00 am

Young blood antiaging trial raises questions (Science)

It was one of the most mind-bending scientific reports in 2014: Injecting old mice with the plasma portion of blood from young mice seemed to improve the elderly rodents’ memory and ability to learn. Inspired by such findings, a startup company has now launched the first clinical trial in the United States to test the antiaging benefits of young blood in relatively healthy people. But there’s a big caveat: It’s a pay-to-participate trial, a type that has raised ethical concerns before, most recently in the stem cell field.

March 17, 2016 9:00 am

Scientists Grow "Dinosaur Legs" in Chicken Embryos

It’s said that dinosaurs went extinct 65 million years ago, but we technically still have dinosaurs running around Earth today (or at least their descendants). Modern-day birds evolved from certain species of dinosaurs, and now scientists have used birds to bring a little piece of the dinosaurs back. In a study published in Evolution, researchers announced that they had successfully grown “dinosaur legs” in chicken embryos.

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