» Clinical Trials & Studies Where the World Finds Bioethics Tue, 22 Apr 2014 22:10:42 +0000 en-US hourly 1 Simple Blood Test To Spot Early Lung Cancer Getting Closer Mon, 07 Apr 2014 20:54:11 +0000 0 Breast Ca Growth Slowed by CDK4/6 Inhibitors Mon, 07 Apr 2014 20:52:29 +0000 0 Guidance published on informing study participants about findings with potential health implications Wed, 02 Apr 2014 18:17:26 +0000 0 Cute with a Good Story: Social Media Selects Experimental Subjects Tue, 01 Apr 2014 19:20:10 +0000 by Craig Klugman, Ph.D.

For patients with a serious illness, accessing cutting edge drugs has just taken a new turn. In the past, a patient with cancer would undergo conventional treatments. If that failed, then he or she would be considered for a clinical trial of a new drug that may (or may not) have the potential to affect the disease. Entry into trials is strict with controls for potential subjects’ age, sex, type and stage of cancer, treatments already tried, and more.…

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Crowdsourcing medical decisions: Ethicists worry Josh Hardy case may set bad precedent Mon, 24 Mar 2014 18:34:20 +0000 0 The Ethics of Advertising for Health Care Services Wed, 19 Mar 2014 19:26:00 +0000 0 Saturated fat advice ‘unclear’ Mon, 17 Mar 2014 23:01:46 +0000 0 Choosing Wisely: Promising New Tests to Diagnose Alzheimer’s Disease Wed, 12 Mar 2014 00:00:55 +0000 by Craig Klugman, Ph.D.

According to an article in Nature Medicine, a new blood test appears to be accurate for diagnosing whether an individual is likely to develop Alzheimer’s disease. Although not yet available for public use, the technique may offer a faster, cheaper, easier, and less invasive method for diagnosis. The researchers looked for fats present in the blood of seniors in the subject pool who were diagnosed with Alzheimer’s disease. Five years earlier, this group, along with others, had a baseline blood draw performed.…

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One Author of a Startling Stem Cell Study Calls for Its Retraction Tue, 11 Mar 2014 18:11:23 +0000 0 Elizabeth Warren vows fight for gender equality in medical studies Tue, 11 Mar 2014 18:10:22 +0000 0 New Clues To Why Traffic Pollution Is So Bad For The Heart Mon, 10 Mar 2014 18:42:29 +0000 0 Free Birth Control Not Associated With Risky Sexual Behavior Mon, 10 Mar 2014 18:38:54 +0000 0 Tampering With Evolution? “Three Parent Embryos” Tue, 04 Mar 2014 23:14:02 +0000 by Maurice Bernstein, MD

Babies are born with  a progressive neurometabolic disorder with a general onset in infancy or childhood, often after a viral infection, but can also occur in teens and adults.  The disease is seen on MRI as dead or dying tissue within the brain and though the child appears normal at birth,  in a few months to two years of age, though earlier or later,  there is loss of basic skills and finally the child may have  heart, kidney, vision and breathing complications. …

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Smoking tied to changes in the structure of teen brains Mon, 03 Mar 2014 21:20:55 +0000 0 Women Still Left Out of Medical Research: Report Mon, 03 Mar 2014 21:08:33 +0000 0 Obesity Drops Among Young Children in U.S., Report Says Wed, 26 Feb 2014 17:51:44 +0000 0 Sitting linked to increased risk for disability, study shows Wed, 19 Feb 2014 19:19:06 +0000 0 Antioxidants including vitamin E can promote lung cancer: study Wed, 29 Jan 2014 20:25:09 +0000 0 Compounds in exhaled breath may detect early lung cancer Tue, 28 Jan 2014 22:07:33 +0000 0 Vitamin D Blog: Protection Is Futile Fri, 24 Jan 2014 19:49:29 +0000 0 Sunshine may chase the blood pressure woes away Thu, 23 Jan 2014 23:02:52 +0000 0 Quality Improvement Ethics: Lessons From the SUPPORT Study Thu, 12 Dec 2013 19:20:51 +0000 0 Informed Consent and Standard of Care: What Must Be Disclosed Thu, 12 Dec 2013 19:18:58 +0000 0 What Should Be Disclosed to Research Participants? Thu, 12 Dec 2013 19:16:39 +0000 0 The SUPPORT Controversy and the Debate Over Research Within the Standard of Care Thu, 12 Dec 2013 19:03:50 +0000 0 Where Have All the Negative Results Gone? Wed, 04 Dec 2013 22:57:29 +0000 by Craig M. Klugman, PhD

This week I gave a lecture at a university in Texas on ways to teach research ethics. A question from the audience led to a conversation about the stresses and pressures that lead researchers to be involved with ethically questionable activities. I mentioned that among the pressures are to maintain and increase funding as well as to get published. This pressure manifests itself in the fact that we are more likely to publish positive results than negative.…

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Addressing Unapproved Meningitis Vaccine at Princeton Mon, 18 Nov 2013 16:16:39 +0000 by Arthur L. Caplan, PhD

Emergency doses of a meningitis vaccine not approved for use in the U.S. are likely to be on the way to Princeton University to halt a meningitis outbreak that has already sickened seven students  There are approved meningitis vaccines available, but they do not protect against Meningitis B—a strain not covered by the shots given in the U.S. and not a strain prevalent here.

Government health officials said Friday they have agreed to import Bexsero, a vaccine licensed only in Europe and Australia that does protect against meningitis B. …

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Binge and Vac: Clinical Trial for Stomach Vacuum Fri, 11 Oct 2013 06:48:02 +0000 by Craig Klugman, Ph.D.

Imagine eating a big meal. You start with the shrimp appetizer, followed by a rich and creamy clam chowder, and a Caesar salad. Your main course is a large steak with buttered mashed potatoes and finished with a big piece of German chocolate cake. You may have consumed 2,000 calories or more in one meal and most people would probably feel stuffed. But not you. Instead you take out your handy aspiration device, connect it to your reverse percutaneous endoscopic gastrostomy (PEG tube) and flip on the vacuum.…

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An Unhealthy Shutdown Thu, 10 Oct 2013 06:45:55 +0000 by Craig Klugman, PhD.

It’s week 2 of the government shutdown with no end in sight. In fact, some people are saying this is a good thing because it achieves their aim of shrinking government. Some Congressmen want the country to go off the deep end of the fiscal cliff, not believing that it would have negative repercussions for the population. The problem is that it turns out the government actually helps protect our health.

Thinking about having some meat for dinner?…

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Texas woman with cancer pressuring experimental drug maker for “compassionate” access Mon, 23 Sep 2013 19:47:12 +0000 0 New scan may diagnose Alzheimer’s as brain changes occur Fri, 20 Sep 2013 17:02:11 +0000 0 DNA and Newborn Screening Sun, 15 Sep 2013 21:27:16 +0000 by Craig Klugman, Ph.D.

The National Institutes of Health wants to know the DNA of our babies.  The government is not looking to diagnose babies and help them live better lives. The NIH wants to know if it’s economically feasible to scan the DNA of every newborn and what social/ethical implications of that would be. Toward that end, the NIH is funding $25 million dollars over the next five years with four, $5million grants already awarded. These grants will examine the economics, health, privacy, and interpersonal issues in newborn genomic screening.…

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Holy Water May be Harmful to Your Health, Study Finds Sat, 14 Sep 2013 16:48:05 +0000 0 E-cigarettes: Healthy tool or gateway device? Thu, 12 Sep 2013 22:06:00 +0000 0 Faster Than the Speed of Thought Fri, 30 Aug 2013 06:36:46 +0000 by Craig Klugman, Ph.D.

In the 1983 comedic film, The Man with Two Brains,”  Steve Martin’s character falls in love with a female brain preserved in a jar. The brain can communicate with Martin and they fall in love. Similarly, in the world of the soon-to-be-retired cartoon “Futurama,” most celebrities and politicians are kept as heads in a jar after death, where they can speak, eat, and even run the country.

On July 1, President Obama requested that the Presidential Commission for the Study of Bioethical Issues “identify a set of core ethical standards—both to guide neuroscience research and to address some of the ethical dilemmas that may be raised by the application of neuroscience research findings.” This request is part of his BRAIN Initiative (Brain Research through Advancing Innovative Neurotechnologies) that was announced April 2.…

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Stem-Cell Heart Repair Questioned Mon, 08 Jul 2013 21:30:55 +0000 0 Study links food-packaging chemical and obesity in girls Fri, 14 Jun 2013 17:16:49 +0000 0 Toxic Lipstick? Metals In Some Lip Products May Be Dangerous, Study Says Thu, 02 May 2013 19:59:17 +0000 0 Stanford study says MRI scans can predict outcome of math tutoring Tue, 30 Apr 2013 16:37:36 +0000 0 Autism Can Be Detected Early By Examining Placenta At Birth, Study Shows Thu, 25 Apr 2013 18:01:17 +0000 0 Live fast, die young: Famous entertainers and athletes average shorter life spans than the rest of us Thu, 18 Apr 2013 19:34:28 +0000 0 Babbling Sounds of Monkeys Share Rhythms with Human Speech Fri, 12 Apr 2013 17:17:11 +0000 0 OHRP throws a wet blanket on comparative effectiveness research Fri, 12 Apr 2013 15:20:19 +0000 David Magnus, PhD

When we go to the doctor and they recommend a treatment, we like to believe that there is good evidence that it is the best treatment available. The reality is that there are often several treatment options (different drugs, different dosing, different procedures) and which treatment you get may depend upon who your doctor is (Dr. A is sure drug X is better while Dr. B thinks drug Y is better—though neither view is well supported by the evidence).…

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Most teens well down road to heart disease, study finds Mon, 01 Apr 2013 17:12:47 +0000 0 Simple Breath Test Might Diagnose Heart Failure Mon, 25 Mar 2013 23:23:05 +0000 0 False-positive mammograms take mental toll, study finds Tue, 19 Mar 2013 22:13:43 +0000 0 Opening Veins Does Not Help Multiple Sclerosis Patients Mon, 18 Mar 2013 21:09:12 +0000 0 ‘Franken-Tadpoles’ See With Eyes on Their Backs Thu, 28 Feb 2013 19:19:35 +0000 0 Breast cancer among young women increasing Wed, 27 Feb 2013 23:38:09 +0000 0 Thousands of women die from breast cancer caused by drinking: research Fri, 15 Feb 2013 17:51:45 +0000 0