Hot Topics: Genetics

Blog Posts (19)

April 19, 2014

Reflections on the Metaphors We Live–and Die–By

Images powerfully impact how we think and how we live. Metaphors, those images we use to describe the indescribable, to portray the unfamiliar and mysterious, are particularly so because of the identity relationships they create. In my last post, I commented on an article in the NYT entitled, “A Tumor: the Embryo’s Evil Twin,” which described the similarities between embryogenesis and the cellular behavior of... // Read More »
March 11, 2014

Choosing Wisely: Promising New Tests to Diagnose Alzheimer’s Disease

by Craig Klugman, Ph.D.

According to an article in Nature Medicine, a new blood test appears to be accurate for diagnosing whether an individual is likely to develop Alzheimer’s disease.…

March 4, 2014

Tampering With Evolution? "Three Parent Embryos"

by Maurice Bernstein, MD

Babies are born with  a progressive neurometabolic disorder with a general onset in infancy or childhood, often after a viral infection, but can also occur in teens and adults. …

January 21, 2014

Building the Better Baby

by Craig Klugman, Ph.D.

In the 1997 film GATTACA, a couple anxious to have a child sit down with their doctor.…

November 26, 2013

The FDA and Home DNA Testing

by Craig Klugman, Ph.D.

For those on the cutting edge (or as we called it in tech journalism, “the bleeding edge”) of science, the Human Genome Project’s promise could be found in home genetic testing.…

September 15, 2013

DNA and Newborn Screening

by Craig Klugman, Ph.D.

The National Institutes of Health wants to know the DNA of our babies.  The government is not looking to diagnose babies and help them live better lives.…

May 6, 2013

“Donor Dad” or “Gene”? The Language of False Hopes and False Expectations

Nanette Elster, JD, MPH

With Mother’s Day rapidly approaching, I can’t help but reflect upon my own journey to motherhood, which began as a solo endeavor with an anonymous sperm donor due to an infertility diagnosis at 30. …

May 3, 2013

Check out AJOB's newest publication 13(5)!

Editorial

Military Doctors and Deaths by Torture: When a Witness Becomes an Accessory
Steven H. Miles

Target Articles

Ban the Sunset?

April 17, 2013

DNA, Patents and the Supreme Court

Craig Klugman, PhD

In 1994, researchers at the University of Utah discovered that mutations in the genes BRCA1 and 2 correlated with higher rates of breast and ovarian cancer.…

January 25, 2013

Whose DNA is it anyway?

Craig Klugman, Ph.D.

The 1000 Genomes Project has collected anonymous DNA samples from people all over the world. By looking at this massive data set, the project hopes to discover genetic components of diseases or traits.…

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Published Articles (39)

American Journal of Bioethics: Volume 14 Issue 3 - Mar 2014

Addressing the Ethical Challenges in Genetic Testing and Sequencing of Children Ellen Wright Clayton, Laurence B. McCullough, Leslie G. Biesecker, Steven Joffe, Lainie Friedman Ross, Susan M. Wolf & For the Clinical Sequencing Exploratory Research (CSER) Consortium Pediatrics Working Group

American Journal of Bioethics: Volume 14 Issue 3 - Mar 2014

Ethics and Empiricism in the Formation of Professional Guidelines Mildred K. Cho

American Journal of Bioethics: Volume 13 Issue 10 - Oct 2013

Gender Eugenics? The Ethics of PGD for Intersex Conditions Robert Sparrow

American Journal of Bioethics: Volume 13 Issue 10 - Oct 2013

Critically Appraising Prenatal Genetic Diagnosis to Prevent Disorders of Sexual Development: An Opportunity Missed Laurence B. McCullough

American Journal of Bioethics: Volume 13 Issue 5 - May 2013

The Right to Know Your Genetic Parents: From Open-Identity Gamete Donation to Routine Paternity Testing An Ravelingien & Guido Pennings

American Journal of Bioethics: Volume 13 Issue 2 - Feb 2013

Do Researchers Have an Obligation to Actively Look for Genetic Incidental Findings? Catherine Gliwa & Benjamin E. Berkman

American Journal of Bioethics: Volume 13 Issue 2 - Feb 2013

What To Do With the Could-Be-Knowns of Genomic Medicine Richard R. Sharp

American Journal of Bioethics: Volume 12 Issue 10 - Oct 2012

Review of Marion Danis, Emily Largent, David Wendler, Sara Chandros Hull, Seema Shah, Joseph Millum, Benjamin Berkman, and Christine Grady, Research Ethics Consultation: A Casebook Emily E. Anderson

American Journal of Bioethics: Volume 12 Issue 4 - Apr 2012

Swabbing Students: Should Universities Be Allowed to Facilitate Educational DNA Testing? Shawneequa L. Callier

American Journal of Bioethics: Volume 12 Issue 4 - Apr 2012

The Case for a Parental Duty to Use Preimplantation Genetic Diagnosis for Medical Benefit Janet Malek & Judith Daar

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News (754)

April 17, 2014 5:42 pm

French School Carries out DNA Dragnet in Rape Case

French investigators began taking DNA samples Monday from 527 male students and staff at a high school — including boys as young as 14 — as they searched for the assailant who raped a teenage girl on the closed campus.

April 3, 2014 4:43 pm

An FDA Update For 23andMe Customers

Over the last few months we’ve heard from many of you asking about where 23andMe stands in the FDA authorization process, so here is the latest.

April 2, 2014 2:15 pm

Scientists hail synthetic chromosome advance

Previously synthetic DNA has been designed and made for simpler organisms such as bacteria.  As a form of life whose cells contain a nucleus, yeast is related to plants and animals and shares 2,000 genes with us.

March 27, 2014 5:42 pm

Gene Gurus Create Synthetic Yeast Chromosome From Scratch

Geneticists say they’ve built a working yeast chromosome from the bottom up for the first time — a feat that could open the way for custom-made biofactories that churn out fuels and pharmaceuticals.

March 26, 2014 4:03 pm

Scientists publish "navigation maps" for human genome

A large international team of scientists has built the clearest picture yet of how human genes are regulated in the vast array of cell types in the body – work that should help researchers target genes linked to disease.

March 24, 2014 6:38 pm

Cardiff University thyroid IQ theory 'could help children'

Children at risk of developing a low IQ could be helped by genetic screening, Cardiff University researchers say.

March 18, 2014 2:49 pm

His Fertility Advance Draws Ire

To most people, the word “mitochondria” is only dimly familiar.  But to Shoukhrat Mitalipov, the mysterious power producers inside every human cell are a lifelong obsession.

March 12, 2014 4:17 pm

Cheap, reliable whole-genome sequencing? Not so fast, say Stanford researchers

A Stanford study found that producing accurate genome analysis is still best left to medical professionals and complete, reliable results from an off-the-shelf test are currently not possible.

March 6, 2014 7:27 pm

A Powerful New Way to Edit DNA

In the late 1980s, scientists at Osaka University in Japan noticed unusual repeated DNA sequences next to a gene they were studying in a common bacterium. They mentioned them in the final paragraph of a paper: “The biological significance of these sequences is not known.”

March 4, 2014 6:13 pm

China Cracks Down on DNA Testing

Genetic testing has grown to be a business big enough in China to warrant the government’s intervention.

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