Bioethics.net » Genetics http://www.bioethics.net Where the World Finds Bioethics Fri, 01 Jul 2016 16:24:34 +0000 en-US hourly 1 First CRISPR Human Clinical Trial Gets a Green Light from the U.S. http://www.bioethics.net/news/first-crispr-human-clinical-trial-gets-a-green-light-from-the-u-s/ http://www.bioethics.net/news/first-crispr-human-clinical-trial-gets-a-green-light-from-the-u-s/#comments Fri, 24 Jun 2016 12:00:53 +0000 http://www.bioethics.net/?post_type=news&p=59557 http://www.bioethics.net/news/first-crispr-human-clinical-trial-gets-a-green-light-from-the-u-s/feed/ 0 Testing, testing: Prenatal genetic screening http://blogs.tiu.edu/bioethics/2016/06/10/testing-testing-prenatal-genetic-screening/ http://blogs.tiu.edu/bioethics/2016/06/10/testing-testing-prenatal-genetic-screening/#comments Fri, 10 Jun 2016 13:01:21 +0000 http://blogs.tiu.edu/bioethics/?p=6765 Read More »]]> http://blogs.tiu.edu/bioethics/2016/06/10/testing-testing-prenatal-genetic-screening/feed/ 0 Mitochondrial replacement boosterism http://blogs.tiu.edu/bioethics/2016/06/09/mitochondrial-replacement-boosterism/ http://blogs.tiu.edu/bioethics/2016/06/09/mitochondrial-replacement-boosterism/#comments Fri, 10 Jun 2016 03:57:47 +0000 http://blogs.tiu.edu/bioethics/?p=6763 Read More »]]> http://blogs.tiu.edu/bioethics/2016/06/09/mitochondrial-replacement-boosterism/feed/ 0 National Academies on Gene-Drives http://feedproxy.google.com/~r/ABlogOnBioethics/~3/q3icJilv19M/national-academies-on-gene-drives.html http://feedproxy.google.com/~r/ABlogOnBioethics/~3/q3icJilv19M/national-academies-on-gene-drives.html#comments Fri, 10 Jun 2016 01:57:00 +0000 http://www.bioethics.net/?guid=beced1c65b658498878e7f290a88d910 http://ablogonbioethics.blogspot.com/feeds/4663769527934801202/comments/default 0 Families Isolated By Rare Genetic Conditions Find New Ways To Reach Out http://www.bioethics.net/news/families-isolated-by-rare-genetic-conditions-find-new-ways-to-reach-out/ http://www.bioethics.net/news/families-isolated-by-rare-genetic-conditions-find-new-ways-to-reach-out/#comments Mon, 06 Jun 2016 12:48:11 +0000 http://www.bioethics.net/?post_type=news&p=59371 http://www.bioethics.net/news/families-isolated-by-rare-genetic-conditions-find-new-ways-to-reach-out/feed/ 0 Scientists Announce HGP-Write, Project to Synthesize the Human Genome http://www.bioethics.net/news/scientists-announce-hgp-write-project-to-synthesize-the-human-genome/ http://www.bioethics.net/news/scientists-announce-hgp-write-project-to-synthesize-the-human-genome/#comments Fri, 03 Jun 2016 13:48:27 +0000 http://www.bioethics.net/?post_type=news&p=59355 http://www.bioethics.net/news/scientists-announce-hgp-write-project-to-synthesize-the-human-genome/feed/ 0 Upcoming Update on Human Gene Editing http://blogs.tiu.edu/bioethics/2016/06/02/upcoming-update-on-human-gene-editing/ http://blogs.tiu.edu/bioethics/2016/06/02/upcoming-update-on-human-gene-editing/#comments Thu, 02 Jun 2016 14:27:47 +0000 http://blogs.tiu.edu/bioethics/?p=6741 Read More »]]> http://blogs.tiu.edu/bioethics/2016/06/02/upcoming-update-on-human-gene-editing/feed/ 0 Deliberating Over Ending Two Species When We Are Bringing Tens of Thousands to the Brink of Extinction http://www.bioethics.net/2016/06/deliberating-over-ending-two-species-when-we-are-bringing-tens-of-thousands-to-the-brink-of-extinction/ http://www.bioethics.net/2016/06/deliberating-over-ending-two-species-when-we-are-bringing-tens-of-thousands-to-the-brink-of-extinction/#comments Wed, 01 Jun 2016 21:48:17 +0000 http://www.bioethics.net/?p=59335 by Craig Klugman, Ph.D.

One of the first news articles I ever wrote in journalism was as an intern at Stanford Magazine. This piece was on research into a human vaccine that would do nothing for us, but would kill any mosquito who happened to bite an inoculated person. The researcher’s ethical question at the time was whether anyone would consent to getting a vaccine that does nothing for her or his personal health.

Twenty-five years later, and this month Smithsonian Magazine published an article on CRISPR-9 gene-editing techniques that will allow for the eradication of mosquitoes.  …

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A Bump on the Road to “3-Parent Babies” http://blogs.tiu.edu/bioethics/2016/05/26/a-bump-on-the-road-to-3-parent-babies/ http://blogs.tiu.edu/bioethics/2016/05/26/a-bump-on-the-road-to-3-parent-babies/#comments Fri, 27 May 2016 04:06:43 +0000 http://blogs.tiu.edu/bioethics/?p=6736 Read More »]]> http://blogs.tiu.edu/bioethics/2016/05/26/a-bump-on-the-road-to-3-parent-babies/feed/ 0 Roundup Ready® Humans http://blogs.tiu.edu/bioethics/2016/05/20/roundup-ready-humans/ http://blogs.tiu.edu/bioethics/2016/05/20/roundup-ready-humans/#comments Fri, 20 May 2016 20:26:27 +0000 http://blogs.tiu.edu/bioethics/?p=6705 Read More »]]> http://blogs.tiu.edu/bioethics/2016/05/20/roundup-ready-humans/feed/ 0 Fabricating Man http://blogs.tiu.edu/bioethics/2016/05/19/fabricating-man/ http://blogs.tiu.edu/bioethics/2016/05/19/fabricating-man/#comments Fri, 20 May 2016 04:48:52 +0000 http://blogs.tiu.edu/bioethics/?p=6703 Read More »]]> http://blogs.tiu.edu/bioethics/2016/05/19/fabricating-man/feed/ 0 Taking a ride down the slippery slope http://www.amc.edu/BioethicsBlog/post.cfm/taking-a-ride-down-the-slippery-slope http://www.amc.edu/BioethicsBlog/post.cfm/taking-a-ride-down-the-slippery-slope#comments Mon, 16 May 2016 15:09:18 +0000 http://www.amc.edu/BioethicsBlog/post.cfm/taking-a-ride-down-the-slippery-slope

Did you know: we can now make sperm from embryonic stem cells (in mice).  Not only can we create this sperm, but we can use it to successfully fertilize an egg and develop into a fully grown mouse.  And what is the role of bioethics in this scientific discovery, according to the article?  A brief mention of theoretical ethical issues relegated to the end of the news article that no one reads far enough to see, anyway.

 

Scientific advancements in reproduction have occurred at an unbelievable rate.  We not only have the ability to create sperm, but we can also create an embryo using three genetic donors, choose or reject embryos based on their genetic traits, such as sex, and correct genetic defects by essentially cutting and pasting healthy DNA sequences over defective ones.  Conversely, using such technology, we also have the potential to clone human beings, choose or reject embryos based on traits such as hair color or athletic ability, and irreversibly alter a germ cell line, potentially leading to unknown negative effects in later generations.

 

While breakthroughs in reproductive technologies have the potential to address issues as important and varied as male infertility, uterine factor infertility, mitochondrial disease, genetic defects and disease, and even artificial gestation, one wonders whether anyone is stopping to ask: to what end?  How will we use this technology?  What are the short- and long-term effects?  How might this technology be misused?  And, my personal favorite, when will we start to regulate how and when we tinker with biology at a genetic level?

 

Despite the promise of treatment or eradication of genetic diseases using this technology, there is still a persistent and very realistic fear that this technology will be misused.  Even worse, the misuse may become so common as to be considered acceptable, particularly in our profit-driven fertility industry.  Will the desire to prevent Huntington’s disease also lead to the desire to enhance intelligence?  Can we really resist the urge to create so-called designer babies, and should we accept that while some may win the genetic lottery, others will be able to afford to stack the deck?

 

Bioethicists are sometimes viewed as obstructionists on the path of progress, unnecessarily blocking scientists from discovering all that can be accomplished through science and medicine. (For an excellent rebuttal, read here).  But the very purpose of the vast and diverse field of bioethics is to identify and acknowledge the normative implications of scientific advances and engage in a dialogue that directly addresses the “should” in a world of “could.”  Hence, the age-old question that is often asked but rarely answered: just because we can do it, does it mean we should?

 

In the world of reproductive technologies and germline manipulation, perhaps the answer, sometimes, is no.

 

 

The Alden March Bioethics Institute offers a Master of Science in Bioethics, a Doctorate of Professional Studies in Bioethics, and Graduate Certificates in Clinical Ethics and Clinical Ethics Consultation. For more information on AMBI's online graduate programs, please visit our website.

 

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Researcher under fire for New Yorker epigenetics article http://www.bioethics.net/news/researcher-under-fire-for-new-yorker-epigenetics-article/ http://www.bioethics.net/news/researcher-under-fire-for-new-yorker-epigenetics-article/#comments Tue, 10 May 2016 12:07:20 +0000 http://www.bioethics.net/?post_type=news&p=59085 http://www.bioethics.net/news/researcher-under-fire-for-new-yorker-epigenetics-article/feed/ 0 Slouching Towards Gattaca http://blogs.tiu.edu/bioethics/2016/04/30/slouching-towards-gattaca/ http://blogs.tiu.edu/bioethics/2016/04/30/slouching-towards-gattaca/#comments Sat, 30 Apr 2016 18:54:35 +0000 http://blogs.tiu.edu/bioethics/?p=6683 Read More »]]> http://blogs.tiu.edu/bioethics/2016/04/30/slouching-towards-gattaca/feed/ 0 A Bit More about the Minimal Genome http://blogs.tiu.edu/bioethics/2016/04/28/a-bit-more-about-the-minimal-genome/ http://blogs.tiu.edu/bioethics/2016/04/28/a-bit-more-about-the-minimal-genome/#comments Fri, 29 Apr 2016 04:48:15 +0000 http://blogs.tiu.edu/bioethics/?p=6681 Read More »]]> http://blogs.tiu.edu/bioethics/2016/04/28/a-bit-more-about-the-minimal-genome/feed/ 0 Genetic Prime Patterns http://blogs.tiu.edu/bioethics/2016/04/26/genetic-prime-patterns/ http://blogs.tiu.edu/bioethics/2016/04/26/genetic-prime-patterns/#comments Tue, 26 Apr 2016 16:21:36 +0000 http://blogs.tiu.edu/bioethics/?p=6660 Read More »]]> http://blogs.tiu.edu/bioethics/2016/04/26/genetic-prime-patterns/feed/ 0 Public Attitudes about Gene Editing http://blogs.tiu.edu/bioethics/2016/04/21/public-attitudes-about-gene-editing/ http://blogs.tiu.edu/bioethics/2016/04/21/public-attitudes-about-gene-editing/#comments Fri, 22 Apr 2016 03:30:51 +0000 http://blogs.tiu.edu/bioethics/?p=6645 Read More »]]> http://blogs.tiu.edu/bioethics/2016/04/21/public-attitudes-about-gene-editing/feed/ 0 Experimentation on nonviable human embryos http://blogs.tiu.edu/bioethics/2016/04/13/experimentation-on-nonviable-human-embryos/ http://blogs.tiu.edu/bioethics/2016/04/13/experimentation-on-nonviable-human-embryos/#comments Wed, 13 Apr 2016 11:26:05 +0000 http://blogs.tiu.edu/bioethics/?p=6629 Read More »]]> http://blogs.tiu.edu/bioethics/2016/04/13/experimentation-on-nonviable-human-embryos/feed/ 0 How Do ‘Genetic Superheroes’ Overcome Their Bad DNA? 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In April 2015 a team of Chinese scientists reported in a little known journal, Protein & Cell, the use of CRISPR/Cas9 to cleave and then repair the HBB gene in nonviable human embryos. The mutated form of HBB causes B-thalassemia, a potentially fatal blood disease. To say the experiment prompted controversy is an understatement. It was published on the heels of two high-profile commentaries in Nature and Science, both of which urged caution about using CRISPR/Cas9 and other technologies to edit the human germline; the Nature authors went so far as to recommend a stop of experiments precisely like the one reported in Protein & Cell.…

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Human Gene Editing: Half Speed Ahead? http://blogs.tiu.edu/bioethics/2015/12/03/human-gene-editing-half-speed-ahead/ http://blogs.tiu.edu/bioethics/2015/12/03/human-gene-editing-half-speed-ahead/#comments Fri, 04 Dec 2015 05:18:44 +0000 http://blogs.tiu.edu/bioethics/?p=6296 Read More »]]> http://blogs.tiu.edu/bioethics/2015/12/03/human-gene-editing-half-speed-ahead/feed/ 0 This Technology Can Fight Cancer And Create Adorable Mini Pigs. So Why Are Scientists So Worried? http://www.bioethics.net/news/this-technology-can-fight-cancer-and-create-adorable-mini-pigs-so-why-are-scientists-so-worried/ http://www.bioethics.net/news/this-technology-can-fight-cancer-and-create-adorable-mini-pigs-so-why-are-scientists-so-worried/#comments Thu, 03 Dec 2015 23:28:03 +0000 http://www.bioethics.net/?post_type=news&p=57439 http://www.bioethics.net/news/this-technology-can-fight-cancer-and-create-adorable-mini-pigs-so-why-are-scientists-so-worried/feed/ 0 ‘Gene drive’ tool can prevent epidemics — but should it? http://www.bioethics.net/news/gene-drive-tool-can-prevent-epidemics-but-should-it/ http://www.bioethics.net/news/gene-drive-tool-can-prevent-epidemics-but-should-it/#comments Tue, 01 Dec 2015 23:27:11 +0000 http://www.bioethics.net/?post_type=news&p=57355 http://www.bioethics.net/news/gene-drive-tool-can-prevent-epidemics-but-should-it/feed/ 0 Germline Manipulation and Our Future Worlds http://www.bioethics.net/articles/germline-manipulation-and-our-future-worlds/ http://www.bioethics.net/articles/germline-manipulation-and-our-future-worlds/#comments Tue, 01 Dec 2015 18:59:02 +0000 http://www.bioethics.net/?post_type=articles&p=57482 http://www.bioethics.net/articles/germline-manipulation-and-our-future-worlds/feed/ 0 Human Germline CRISPR-Cas Modification: Toward a Regulatory Framework http://www.bioethics.net/articles/human-germline-crispr-cas-modification-toward-a-regulatory-framework/ http://www.bioethics.net/articles/human-germline-crispr-cas-modification-toward-a-regulatory-framework/#comments Tue, 01 Dec 2015 18:58:04 +0000 http://www.bioethics.net/?post_type=articles&p=57481 http://www.bioethics.net/articles/human-germline-crispr-cas-modification-toward-a-regulatory-framework/feed/ 0 Engineering Values Into Genetic Engineering: A Proposed Analytic Framework for Scientific Social Responsibility http://www.bioethics.net/articles/engineering-values-into-genetic-engineering-a-proposed-analytic-framework-for-scientific-social-responsibility/ http://www.bioethics.net/articles/engineering-values-into-genetic-engineering-a-proposed-analytic-framework-for-scientific-social-responsibility/#comments Tue, 01 Dec 2015 18:57:08 +0000 http://www.bioethics.net/?post_type=articles&p=57480 http://www.bioethics.net/articles/engineering-values-into-genetic-engineering-a-proposed-analytic-framework-for-scientific-social-responsibility/feed/ 0 CRISPR Critters and CRISPR Cracks http://www.bioethics.net/articles/crispr-critters-and-crispr-cracks/ http://www.bioethics.net/articles/crispr-critters-and-crispr-cracks/#comments Tue, 01 Dec 2015 18:56:16 +0000 http://www.bioethics.net/?post_type=articles&p=57479 http://www.bioethics.net/articles/crispr-critters-and-crispr-cracks/feed/ 0