Hot Topics: Human Subjects Research & IRBs
The Working Group on Compassionate Use and Preapproval Access (CUPA), a project of the NYU Grossman School of Medicine Division of Medical Ethics
The undersigned are members of a multidisciplinary group comprising bioethicists, clinicians, patient advocates, and representatives from industry and law who for the past seven years have been studying the ethical issues surrounding access to medical products before they have received regulatory approval.…
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by Keisha Ray, Ph.D.
I take the drug hydroxychloroquine, brand name Plaquenil, for an autoimmune disease. Hydroxychloroquine was once used to treat malaria and is now commonly used to treat a range of inflammatory disorders like lupus and rheumatoid arthritis.…
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by Craig Klugman, Ph.D.
Last week, NPR reported on a new pre-publication article published in the journal Human Reproduction (HR).…
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This post appears by special arrangement with the American Journal of Bioethics.
by John D. Lantos, MD
In this issue, Macklin and Natanson examine some of the controversies that arise in randomized clinical trials (RCTs).…
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by Craig Klugman, Ph.D. and Keisha Ray, Ph.D.
The end of the year usually brings a media blitz of top ten lists for the year that is ending.…
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by Marieke Bak, MSc, MA, PhD(c)
When people die nowadays, they no longer leave behind only physical assets. Their estate includes large amounts of personal data that remain in existence after they pass away.…
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by Craig Klugman, Ph.D.
After age 40, the risk of developing a cataract increases. By 75 years of age in the U.S.,…
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by Craig Klugman, Ph.D.
In 1983, NBC broadcast an alien invasion limited series calledV. In one episode, as the U.S.…
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by Craig Klugman, Ph.D.
Move over United States, China is the new research powerhouse. In the last few months, announcements out of China talk about the first live human births from genetically edited embryos; the birth of 5 cloned, genetically edited monkeys, and most recently, announced the development of an artificial intelligencethat is more accurate than human doctors at diagnosing diseases in children.…
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Updated November 28 at 8:30am EST
by Craig Klugman, Ph.D.
The film GATTACA turned 20 years old this year. The premise of that film is a society where DNA is viewed as predictive of everything: Your intelligence, physical abilities, your health, even how long you will live.…
Full ArticleHuman Brain Surrogates Research: The Onrushing Ethical Dilemma
Patient and Family Descriptions of Ethical Concerns
Partnering With Patients to Bridge Gaps in Consent for Acute Care Research
The Role of Solidarity in Research in Global Health Emergencies
Better Consent—and Not Just for When Time Is Short
Clearing Muddy Waters: The Need to Reconceptualize Minor Increase over Minimal Risk in Pediatric Rare Disease Research
Can the Principles of Research Ethics Help Us Distribute Clinical Resources More Fairly?
Misrepresenting “Usual Care” in Research: An Ethical and Scientific Error
Ethics and Collateral Findings in Pragmatic Clinical Trials
What are some opinions on the ethics of CRISPR? “Doudna herself recognizes that CRISPR carries with it “great risk….but she warned of the unknown consequences of embryo editing, cautioning researchers to wait to use CRISPR for these ends.”
Full ArticleWhat does the future of human genomics and equity look like? “This special issue of Nature examines how far the human genome sequence has taken us, and how far we have to go.”
Full ArticleWhat drives vaccine hesitancy among healthcare workers? “The hesitancy is less outright rejection than cautious skepticism. It’s driven by suspicions about the evidence supporting the new vaccines and about the motives of those endorsing them.”
Full ArticleHow can we look to the past to provide insight into our current society? In this piece by Jenny Gross, we take a look at historical mass vaccination campaigns and how past questions can now lead to future answers.
Full ArticleVaccine hesitancy has been an important topic for discussion regarding the #COVID19 vaccine. “How can medical and public health leaders work to overcome this hesitancy? To start with, acknowledge the historical reasons for black mistrust of medicine.”
Full ArticleA big component of vaccine distribution has been utilizing ethics to determine vaccine prioritization. Issac Chotiner of The New Yorker speaks with immunologist Barry Bloom to discuss what goes into making decisions on vaccine distribution.
Full Article“The first year of the Covid-19 pandemic revealed that a country’s wealth would not spare it from the virus. Overconfidence, poor planning and ignored warnings felled the world’s richest nations. But now, money is translating into undeniable advantages.”
Full ArticleThe new COVID-19 variants that have popped up in the United Kingdom and South Africa are the new obstacles to tackle in the pandemic. Will current vaccines be able to measure up against new strains? Scientists are seeking an answer.
Full ArticleWhy has vaccine distribution fallen into disarray across the United States? Lack of funding and coordination between state and local governments has left citizens confused about their vaccination opportunities. What will come in year 2 of COVID-19?
Full ArticleRecent data has shown COVID-19 numbers are trending in the wrong directions for our populations at risk. With the vaccine soon to be rolled out, what needs to be considered in distribution as we look at the effects of COVID-19 on elderly populations?
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