Hot Topics: Reproductive Medicine

Blog Posts (49)

April 1, 2015

Abortion Wars: Arizona Mandates Unscientific “Truths”

by Craig Klugman, Ph.D.

The Arizona legislature has apparently gone through medical school and graduated. They have passed a new law of the land.…

March 18, 2015

Frankenstein babies and designer babies? Ethical concerns raised by “3 person embryos”

<p style="font-size: 11.1999998092651px; line-height: 19.0400009155273px;"><a href="http://www.popsci.com/uk-one-step-closer-using-dna-3-people-make-babies">The story</a> about the UK passing a law to allowa reproductive technology called mitochondrial donation, what has been informally known as three person or three parent embryos, recently dominated the news.Part of the reason this story received so much attention is because the idea of a child with more than two biological parents sounds really scary, even Frankensteinish.While new medical technologies often raise ethical concerns, it is imperative to understand the science behind these technologies in order to accurately assess the likelihood and degree of potential harms caused by these technologies. In the case of three parent embryos, once we understand the science, this technology is not as threatening as it may initially appear.</p> <p style="font-size: 11.1999998092651px; line-height: 19.0400009155273px;"><span style="font-size: 11.1999998092651px; line-height: 19.0400009155273px;">The UK will only allow mitochondrial donations in cases where women could pass along mitochondrial diseases to their children. There are various types of mitochondrial diseases, which affect approximately one in 8,500 people and can lead to serious and fatal conditions. The mitochondria are located in the cytoplasm of the cell and serve as the cell powerhouses. Mitochondria have their own set of DNA with the 37 genes and a mitochondrial disease occurs when there is a mutation in the mitochondrial DNA. Mitochondrial donation allows women who are at risk for passing along mitochondrial diseases to the children to avoid doing so by using the mitochondria of a donor. There are two ways this can be done. In the first way, known asmaternal spindle transfer technique, the nucleus from the donor egg is removed and replaced with the nucleus from the intended mother's egg. The resultant eggwill carry the nucleus with all the genetic information from the intended mother, but will also contain the healthy mitochondrial DNA from the donor egg.The second way, known as pronuclear transfer, removes the nucleus from a donor embryo and replaces it with the nucleus of an embryo that contains the genetic material from intended mother and father. Here again,the resultant embryo contains the genetic material from the intended parents, but avoids inheriting mitochondrial diseases because donor mitochondria is used. </span></p> <p><strong style="color: #34405b; font-family: Arial, Helvetica, sans-serif; font-size: 12px; line-height: 19.0400009155273px;">The Alden March Bioethics Institute offers a Master of Science in Bioethics, a Doctorate of Professional Studies in Bioethics, and Graduate Certificates in Clinical Ethics and Clinical Ethics Consultation. For more information on AMBI's online graduate programs, please visit our <a style="color: #000099; text-decoration: underline;" href="http://www.amc.edu/Academic/bioethics/index.cfm">website</a>.</strong><span style="color: #34405b; font-family: Arial, Helvetica, sans-serif; font-size: 12px; line-height: 19.0400009155273px;"> </span></p>
March 16, 2015

Ethics of Penile Transplants

by Craig Klugman, Ph.D.

This weekend, doctors in South Africa announced a new first—a successful penis transplant. The 9-hour operation took place in December 2014.…

February 17, 2015

Men's reproductive health: Neglected in policy and practice

<div style="font-size: 11.1999998092651px; line-height: 19.0400009155273px;">In recognizing the health-related and financial benefits of preventive reproductive health services, the Affordable Care Act (ACA) has included them (namely contraception and preconception care) as part of standard care and without co-payment. While the inclusion of women’s reproductive health care in the ACA is a milestone for women’s health, children’s health, and reproductive health overall, it is troubling that the ACA does not seem to make any mention of men’s reproductive health</div> <div style="font-size: 11.1999998092651px; line-height: 19.0400009155273px;"><br /></div> <div style="font-size: 11.1999998092651px; line-height: 19.0400009155273px;">Men's reproductive health is not only missing from policy, also from everyday practice. Whereas women know to see a gynecologist for their reproductive health and can easily do, men are often unsure of where to turn for the reproductive health needs. Most men have never heard of the field of andrology, which is devoted to men's reproductive health, and this field is so small and fragmented that it may be difficult for a man to find a nearby andrologist. Some men seek out urologists for their reproductive health, but many urologists are not trained in all areas of men's reproductive health. Men may also talk to their primary care physician about their reproductive health needs, but many of these physicians are not very familiar with men's reproductive health since it is barely covered in medical school. Family planning centers tend to focus on treating women and some family planning providers have even been known to be hostile toward men. The lack of healthcare providers trained to treat in men’s sexual and reproductive health contributed to American Board of Obstetrics and Gynecology recent statement that condoned OBGYNs treating certain areas of men’s sexual and reproductive health.</div> <p><strong style="color: #34405b; font-family: Arial, Helvetica, sans-serif; font-size: 12px; line-height: 19.0400009155273px;">The Alden March Bioethics Institute offers a Master of Science in Bioethics, a Doctorate of Professional Studies in Bioethics, and Graduate Certificates in Clinical Ethics and Clinical Ethics Consultation. For more information on AMBI's online graduate programs, please visit our <a style="color: #000099; text-decoration: underline;" href="http://www.amc.edu/Academic/bioethics/index.cfm">website</a>.</strong><span style="color: #34405b; font-family: Arial, Helvetica, sans-serif; font-size: 12px; line-height: 19.0400009155273px;"> </span></p>
January 23, 2015

The Need for Patient Navigators for Fertility Preservation

<p style="line-height: 19.0400009155273px;"><span style="line-height: 19.0400009155273px;">Although life-saving, cancer treatments (e.g. radiation, chemotherapy, and surgery) can also lead to infertility in both women and men. Established reproductive technologies for women and men like gamete freezing and embryo freezing allow cancer patients to preserve their fertility in case they want to become biological parents in the future. </span></p> <p style="line-height: 19.0400009155273px;">Unfortunately, patients are frequently not adequately informed and sometimes not informed at all about fertility preservation. Some oncologists don’t consider fertility preservation to be an important issue, as they are more focused on saving the patients’ lives and see fertility preservation as a secondary consideration. Research has shown that even when oncologists refer their patients for fertility preservation they often do so based on social factors (they are more likely to refer wealthy, white, heterosexual, married patients) rather than purely on medical indications. Even when health care providers discuss fertility preservation with patients, many patients say that once they heard the word “cancer” as a diagnosis, they didn’t absorb much else from their initial conversation with their provider. </p> <p style="line-height: 19.0400009155273px;"><strong style="line-height: 19.0400009155273px; color: #34405b; font-family: Arial, Helvetica, sans-serif; font-size: 12px;">The Alden March Bioethics Institute offers a Master of Science in Bioethics, a Doctorate of Professional Studies in Bioethics, and Graduate Certificates in Clinical Ethics and Clinical Ethics Consultation. For more information on AMBI's online graduate programs, please visit our <a style="text-decoration: underline; color: #000099;" href="http://www.amc.edu/Academic/bioethics/index.cfm">website</a>.</strong><span style="line-height: 19.0400009155273px; color: #34405b; font-family: Arial, Helvetica, sans-serif; font-size: 12px;"> </span></p>
January 16, 2015

In for Life: Procreative Liberty for Incarcerated Persons Serving Prison Sentences

<p class="MsoNormal" style="line-height: 19.0400009155273px;"><span style="line-height: 19.0400009155273px;">The release of Cuban spy Gerardo Hernandez as part of a prisoner swap made headlines last month not only for the diplomatic implications for Cuba-US relations, but also for the questions surrounding assisted reproductive services for incarcerated persons. According to a brief report from </span><a style="line-height: 19.0400009155273px;" href="http://www.npr.org/blogs/thetwo-way/2014/12/22/372525940/cuban-american-not-so-immaculate-conception">NPR</a><span style="line-height: 19.0400009155273px;">, Hernandez’s spouse wanted to have a child with her incarcerated husband and sought support from a sympathetic US senator to facilitate this expression of reproductive liberty. While this case includes an added layer of intrigue because of the impressive barriers that were overcome to secure the means and support for artificial insemination, the question of how we ought to consider the use of assisted reproductive technology for couples who wish to bear children despite one parent serving a life sentence.</span></p> <p class="MsoNormal" style="line-height: 19.0400009155273px;"><span style="line-height: 19.0400009155273px;">While some children may be conceived where prisoners are permitted conjugal visits, Mr. Hernandez was in a federal prison where it is reported that such visits are not allowed. The only means for reproduction would be via assisted technology such as artificial insemination, a now basic intervention. What about other families who wish to raise children but without the connections or possibility for release? Is it ethical to support such endeavors when one parent will be able to contribute gametes and an occasional visit in a prison setting without freedom to participate in rearing the child? This is not such an easily answered question.</span></p> <p><strong style="color: #34405b; font-family: Arial, Helvetica, sans-serif; font-size: 12px; line-height: 19.0400009155273px;">The Alden March Bioethics Institute offers a Master of Science in Bioethics, a Doctorate of Professional Studies in Bioethics, and Graduate Certificates in Clinical Ethics and Clinical Ethics Consultation. For more information on AMBI's online graduate programs, please visit our <a style="color: #000099; text-decoration: underline;" href="/Academic/bioethics/index.cfm">website</a>.</strong><span style="color: #34405b; font-family: Arial, Helvetica, sans-serif; font-size: 12px; line-height: 19.0400009155273px;"> </span></p>
January 6, 2015

Should We License Parents?

<p style="line-height: 19.0400009155273px;"><span style="line-height: 19.0400009155273px;">Many professions require state or federal licensure, including hairdressers, teachers, accountants, and physicians. The main reason we have professional licensure is to protect the clients who seek out the services of these professionals. Licenses require that professionals meet a minimum standard of knowledge and skills to certify competence in their field. Even some leisure activities require licensure, especially those that are considered potentially dangerous, such as scuba diving and hunting. </span></p> <p style="line-height: 19.0400009155273px;">Some have suggested that parents should also be licensed as a way of protecting their children by ensuring that have a base minimum skill set and knowledge about good parenting. The typical response to this suggestion is an emphatic no. Why is our knee jerk reaction to the idea of licensing parents to be horrified when we aren't bothered by licenses for professional and leisure activities, some of which also involve placing the lives of others in their hands (e.g. a physician) or require developing a deeper connection between people (e.g. a teacher)? How and why is parenthood different from these other activities? </p> <p style="line-height: 19.0400009155273px;"><strong style="color: #34405b; font-family: Arial, Helvetica, sans-serif; font-size: 12px; line-height: 19.0400009155273px;">The Alden March Bioethics Institute offers a Master of Science in Bioethics, a Doctorate of Professional Studies in Bioethics, and Graduate Certificates in Clinical Ethics and Clinical Ethics Consultation. For more information on AMBI's online graduate programs, please visit our <a style="color: #000099; text-decoration: underline;" href="/Academic/bioethics/index.cfm">website</a>.</strong><span style="color: #34405b; font-family: Arial, Helvetica, sans-serif; font-size: 12px; line-height: 19.0400009155273px;"> </span></p>
November 19, 2014

The Ethics of Uterus Transplantation

<p><span style="line-height: 19.0400009155273px;">In the last couple of years, the media has reported women undergoing uterus transplantations. Just last month, </span><a style="line-height: 19.0400009155273px;" href="http://www.bbc.com/news/health-29485996">the media reported</a><span style="line-height: 19.0400009155273px;"> that the first baby was born from a transplanted uterus. While the woman’s identity remains unknown, she is a 36 year old Swedish woman who was born with ovaries, but not a uterus. She and her partner underwent IVF to produce embryos that could then be transferred into the transplanted uterus. This donor is a friend of hers who is 61 years old and had experienced menopause seven years beforehand. The quality of a woman’s uterus does not diminish over time, so she is able to successfully carry a pregnancy event postmenopausally (it is the quality and quantity of her eggs that leads to infertility and eventually menopause).  Both the woman and the baby are doing fine, according to media reports. However, the baby was born prematurely at 32 weeks because the women developed preeclampsia and the fetal heart rate became abnormal. It is not clear from the media reports whether the development of preeclampsia was related to the uterus transplantation.</span></p> <p><strong style="line-height: 19.0400009155273px; color: #34405b; font-family: Arial, Helvetica, sans-serif; font-size: 12px;">The Alden March Bioethics Institute offers a Master of Science in Bioethics, a Doctorate of Professional Studies in Bioethics, and Graduate Certificates in Clinical Ethics and Clinical Ethics Consultation. For more information on AMBI's online graduate programs, please visit our <a style="text-decoration: underline; color: #000099;" href="http://www.amc.edu/Academic/bioethics/index.cfm">website</a>.</strong></p>
November 16, 2014

The New Abortion Issue: The Moral Status of Women

<p style="line-height: 19.0400009155273px;"><span style="line-height: 19.0400009155273px;">Let me emphatically state at the outset of this short blog: I have always thought the elective termination of pregnancy (ETOL) was a serious moral issue. As I have taught students over the years on this topic, to fully appreciate the moral conflict around abortion (or any other moral conflict) one must be willing to put oneself in the middle of two important value positions. In other words, one must be willing to hold and take seriously in one’s mind simultaneously two opposing thoughts or value positions in order to weigh them fairly. </span><span style="line-height: 19.0400009155273px;"> </span></p> <p class="MsoNormal" style="line-height: 19.0400009155273px;"><span style="line-height: 19.0400009155273px;">Though I don’t think that a fetus is a person with a personal or social identity, it is biologically human—and that alone is a relevant piece of moral information. The fetus has a unique genetic code and has the potential to grow to full term into a new baby and eventually grow into a child, adolescent, and adult human being. Because a fetus has the potential to become a full-fledged member of the human community, all things equal, we should not destroy it. But rarely in human life are all things equal.</span></p> <p class="MsoNormal" style="line-height: 19.0400009155273px;"><strong style="line-height: 19.0400009155273px; color: #34405b; font-family: Arial, Helvetica, sans-serif; font-size: 12px;">The Alden March Bioethics Institute offers a Master of Science in Bioethics, a Doctorate of Professional Studies in Bioethics, and Graduate Certificates in Clinical Ethics and Clinical Ethics Consultation. For more information on AMBI's online graduate programs, please visit our <a style="text-decoration: underline; color: #000099;" href="/Academic/bioethics/index.cfm">website</a>.</strong></p>
October 22, 2014

The Ethics of Sperm Freezing for Teenage Boys

<p class="MsoNormal" style="line-height: 19.0400009155273px;"><span style="line-height: 19.0400009155273px;">A few weeks ago, I attended the </span><a style="line-height: 19.0400009155273px;" href="http://oncofertility.northwestern.edu/2014-Conference">annual Oncofertility Consortium conference</a><span style="line-height: 19.0400009155273px;"> where Dr. Angel Petropanagos and I presented our poster “Teen Boys and Fertility Preservation: An Ethical Analysis.”</span><span style="line-height: 19.0400009155273px;">  </span><span style="line-height: 19.0400009155273px;">The vast majority of discussions about fertility preservation (FP), particularly FP for “social” (aka nonmedical) reasons, are focused on women in part because FP for women raises more ethical issues.</span><span style="line-height: 19.0400009155273px;">  </span><span style="line-height: 19.0400009155273px;">For instance, egg freezing carries more health risks and is generally less effective than sperm freezing. Furthermore, whereas sperm freezing has been an established method of FP for decades, it was only two years ago that the American Society for Reproductive Medicine lifted the experimental label from egg freezing.</span></p> <p class="MsoNormal" style="line-height: 19.0400009155273px;"><span style="line-height: 19.0400009155273px;">Yet, even established technologies can raise ethical concerns when used in vulnerable groups, such as children. Our research project examines the ethical issues FP raises when used by teenage boys.</span><span style="line-height: 19.0400009155273px;">  </span><span style="line-height: 19.0400009155273px;">In order to undergo sperm freezing, males must produce a sperm sample and this is usually done through masturbation. However, discussions about masturbation can be embarrassing and difficult for adolescent males (as well as for healthcare providers), particularly if they have never masturbated or never masturbated and achieved an ejaculation. Some parents and healthcare providers place a high value on preserving patients’ future option of genetic reproduction, but FP discussions with teen males can be especially challenging due to the sensitive and private nature of sexuality and reproduction. </span></p> <p class="MsoNormal" style="line-height: 19.0400009155273px;"><strong style="line-height: 19.0400009155273px; color: #34405b; font-family: Arial, Helvetica, sans-serif; font-size: 12px;">The Alden March Bioethics Institute offers a Master of Science in Bioethics, a Doctorate of Professional Studies in Bioethics, and Graduate Certificates in Clinical Ethics and Clinical Ethics Consultation. For more information on AMBI's online graduate programs, please visit our <a style="text-decoration: underline; color: #000099;" href="/Academic/bioethics/index.cfm">website</a>.</strong></p>

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Published Articles (21)

American Journal of Bioethics: Volume 15 Issue 2 - Feb 2015

Ritual Male Infant Circumcision and Human Rights Allan J. Jacobs & Kavita Shah Arora

American Journal of Bioethics: Volume 14 Issue 7 - Jul 2014

Therapeutic, Prophylactic, Untoward, and Contraceptive Effects of Combined Oral Contraceptives: Catholic Teaching, Natural Law, and the Principle of Double Effect When Deciding to Prescribe and Use Murray Joseph Casey & Todd A. Salzman

American Journal of Bioethics: Volume 14 Issue 5 - May 2014

Transnational Gestational Surrogacy: Does It Have to Be Exploitative? Jeffrey Kirby

American Journal of Bioethics: Volume 13 Issue 10 - Oct 2013

Gender Eugenics? The Ethics of PGD for Intersex Conditions Robert Sparrow

American Journal of Bioethics: Volume 13 Issue 10 - Oct 2013

Critically Appraising Prenatal Genetic Diagnosis to Prevent Disorders of Sexual Development: An Opportunity Missed Laurence B. McCullough

American Journal of Bioethics: Volume 13 Issue 5 - May 2013

The Right to Know Your Genetic Parents: From Open-Identity Gamete Donation to Routine Paternity Testing An Ravelingien & Guido Pennings

American Journal of Bioethics: Volume 13 Issue 3 - Mar 2013

Expanding Access to Testicular Tissue Cryopreservation: An Analysis by Analogy Tuua Ruutiainen, Steve Miller, Arthur Caplan & Jill P. Ginsberg

American Journal of Bioethics: Volume 12 Issue 7 - Jul 2012

On the Cutting Edge: Ethical Responsiveness to Cesarean Rates Sylvia Burrow

American Journal of Bioethics: Volume 12 Issue 7 - Jul 2012

Ethical Dilemma of Mandated Contraception in Pharmaceutical Research at Catholic Medical Institutions Murray Joseph Casey

American Journal of Bioethics: Volume 12 Issue 7 - Jul 2012

The Professional Responsibility Model of Respect for Autonomy in Decision Making About Cesarean Delivery Frank A. Chervenak & Laurence B. McCullough

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News (663)

April 2, 2015 4:30 pm

DNA Blood Test Accurately Identifies Down Syndrome in Fetus

A DNA-based blood test may be more effective in detecting possible Down syndrome in unborn children compared to other screening methods, according to findings published in the New England Journal of Medicine.

March 30, 2015 6:57 pm

Grants help level the playing field for young moms in science

Thanks to a generous benefactor, young mothers doing laboratory research at the Massachusetts General Hospital in Boston can receive major grants to keep them from falling behind while they raise their children.

March 10, 2015 6:35 pm

Brazil passes femicide law to tackle rise in gender killings

Brazil, where a woman is killed every two hours, is imposing tougher punishments on those who murder women and girls, as part of a government bid to stem a rise in gender killings.

February 12, 2015 4:31 pm

HPV vaccine linked to less-risky behavior

Contrary to concerns that getting vaccinated against human papilloma virus (HPV) will lead young people to have more or riskier sex, a new study in England finds less risky behavior among young women who got the HPV vaccine.

February 9, 2015 4:07 pm

UK Set to Legalize Babies With DNA From 3 Parents

After a parliamentary vote earlier this week, the United Kingdom is set to become the first country to legalize making a baby with DNA from three parents.

January 28, 2015 5:51 pm

Growing human kidneys in rats sparks ethical debate

Researchers say they have developed a new technique that could get more kidneys to people who need transplants, but the method is sure to be controversial: The research shows that it is feasible to remove a kidney from an aborted human fetus, and implant the organ into a rat, where the kidney can grow to a larger size.

 

December 11, 2014 7:24 pm

California study finds abortion complications very rare

Less than one quarter of one percent of abortion procedures result in major complications, a very low rate that is comparable to minor outpatient procedures in the U.S., according to a study of more than 50,000 women.

December 8, 2014 5:55 pm

No increase in risky sexual activity with HPV vaccine

Vaccinating young girls against the sexually transmitted human papillomavirus (HPV) doesn’t lead to an increase in risky sexual activity, a new study shows.

December 3, 2014 3:16 pm

Male circumcision benefits outweigh risks, U.S. CDC says

The benefits of male circumcision outweigh the risks, according a long awaited draft of federal guidelines from U.S. health officials released on Tuesday, which indicate that scientific evidence supports recommending the procedure.

December 2, 2014 3:13 pm

In Senegal, women kill own babies due to strict abortion laws

Strict abortion laws in Senegal are forcing women to seek clandestine abortions and as a last resort kill their own infants, according to a new report by human rights groups.

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