Hot Topics: Research Ethics
by Jing Wan,Yuqiong Huang, Amaneh Abdel Hafez Aljaafreh, Dandan Dong, Yali Cong , Jun Lin, Hongxiang Chen
COVID-19 is an emerging infectious disease that is extremely contagious and can cause serious consequences and even death.
by Katharine Wright & Julian Sheather
Pratt et al. highlight important ways in which solidarity between researchers and communities provides both an ethical underpinning, and an ethical goal, for community engagement in global health research.…
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Double-blind randomized clinical trials are the gold standard for answering the scientific question of whether a drug produces any effect, positive or negative, in Covid-19 patients. But is rational for a patient to choose to try a drug such as chloroquine for Covid-19 outside of a trial? Some patients may correctly hold that they have little to lose.
The post Clinical Trials vs. Right to Try: Ethical Use of Chloroquine for Covid-19 appeared first on The Hastings Center.
Full ArticleWritten by Julian Savulescu and Dominic Wilkinson Cross-posted with the Journal of Medical Ethics blog Altruism is one person sacrificing or risking his or her own interests for another’s interests. Humans, like other animals, have a tendency towards altruism. This is usually directed to members of their own group. An example is donating a kidney […]
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In the rush to find a Covid-19 vaccine and one or more drugs to treat the deadly disease, concerns are being raised that ethical standards for conducting human clinical trials and the evidentiary standards for determining whether interventions are safe and effective, might be loosened.
The post Ethics and Evidence in the Search for a Vaccine and Treatments for Covid-19 appeared first on The Hastings Center.
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by Ariadne A. Nichol, B.A.
Development of experimental vaccines to combat the COVID-19 pandemic has been rapidly progressing. In the United States, several Phase I clinical trial participants already received an injection of mRNA-1273, the experimental vaccine developed by the National Institutes of Health (NIH) and a biotechnology firm called Moderna.…
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by Farid Rahimi, Ph.D. ELS and Amin Talebi Bezmin Abadi, Ph.D.
The first reports of “pneumonia of unknown cause” emerged from the Wuhan City, China, three months ago.…
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by Thibaud Haaser, MD, PhD
The current coronavirus pandemic challenges health care systems, raises ethical questions about health policies, and makes some countries fear or even face dilemmas over the allocation of scarce resources.…
Full ArticleThis essay was the runner up in the undergraduate category of the 6th Annual Oxford Uehiro Prize in Practical Ethics Written by University of Oxford student Toby Lowther In this paper, I discuss the question of whether science can ethically make use of data which has been gathered by unethical means in seeking scientific and […]
Full ArticleBy Julian Savulescu Cross-posted from The Guardian The race is on to find a treatment for coronavirus. This race is split between two approaches: the trialling of pre-existing drugs used for similar diseases, and the hunt for a vaccine. In both instances, important ethical decisions must be made. Is it OK to reassign a treatment that […]
Full ArticlePatient and Family Descriptions of Ethical Concerns
Solidarity and Community Engagement in Global Health Research
Partnering With Patients to Bridge Gaps in Consent for Acute Care Research
The Role of Solidarity in Research in Global Health Emergencies
Better Consent—and Not Just for When Time Is Short
Patenting Foundational Technologies: Recent Developments in the CRISPR Patent Struggle
Clearing Muddy Waters: The Need to Reconceptualize Minor Increase over Minimal Risk in Pediatric Rare Disease Research
From Expectations to Experiences: Consumer Autonomy and Choice in Personal Genomic Testing
Patient’s Perspectives of Experimental HCV-Positive to HCV-Negative Renal Transplantation: Report from a Single Site
Experts are troubled by the apparent lack of informed consent in a large, cluster randomised study of the malaria vaccine.
Full ArticleThe use of crowd workers as research participants is fast becoming commonplace in social, behavioral, and educational research, and institutional review boards are encountering more and more research protocols concerning these workers. In what sense are crowd workers vulnerable as research participants, and what should ethics reviewers look out for in evaluating a crowdsourced research protocol?
Full ArticleBrain organoids, often called “minibrains,” have changed the way scientists study human brain development and disorders like autism. But the cells in these organoids differ from those in an actual brain in some important ways, scientists reported Wednesday in the journal Nature.The finding suggests that scientists need to be cautious about extrapolating results found in organoids to people.
Full ArticleScientists can now create clumps of cells that resemble human embryos, raising hopes that they could study the elusive first stages of human development while avoiding the ethical concerns that make it difficult to study actual human embryos. But US researchers say they are finding it increasingly difficult to obtain federal funding for such work.
Full ArticleResearchers have conducted a controversial study that involved paying dozens of young women at a hospital near Puerto Vallarta, Mexico, to get artificially inseminated so their embryos could be flushed out of their bodies and analyzed for research purposes.
Full ArticleA new genetic engineering technology could help eliminate malaria and stave off extinctions — if humanity decides to unleash it.
Full ArticleThe return is part of a groundbreaking approach that could inspire other institutions grappling with how to use historical samples ethically in research.
Full ArticleHe Jiankui’s work was also carried out on a third infant, according to China’s state media, in a new disclosure that is likely to add to the global uproar over such experiments.
Full ArticleTwo piglets recently born in China look like average swine on the outside, but on the inside, they are (a very small) part monkey.
Full ArticleHe Jiankui’s manuscript shows how he ignored ethical and scientific norms in creating the gene-edited twins Lulu and Nana.
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