Blog Posts (26)
November 21, 2013
[FiercePharma] Google made major waves two months ago when it landed former Genentech CEO Art Levinson to run its still-murky biotech offshoot, Calico. Now the biotech elder statesman is reuniting with his former chief medical officer, convincing Hal B...
November 20, 2013
[Science Daily ] Almost one in three (29%) large clinical trials remain unpublished five years after completion. And of these, 78% have no results publicly available, finds a new study.This means that an estimated 250,000 people have been exposed to th...
November 19, 2013
Here is an article that I wrote for the Hastings Center Report describing the problem of missing and misleading information about our medicines and what to do about it.
Abstract. In 1971, President Richard Nixon declared a “war against cancer,
November 18, 2013
[Nature, Abstract] Drugs are approved by regulatory agencies on the basis of their assessment of whether the available evidence indicates that the benefits of the drug outweigh its risks. In recent years, regulatory agencies have been criticized both f...
November 2, 2013
[The Guardian] Almost a third of large clinical trials in the US still not published five years after being finished, scientists write in BMJ
Scientists say about 250,000 people have taken part in unpublished trials and have therefore been exposed to ...
April 6, 2013
[THE BLOG OF THE PRESIDENTIAL COMMISSION FOR THE STUDY OF BIOETHICAL ISSUES] Most pediatric research can be approved by an institutional review board (IRB) if it poses only minimal risk, offers the prospect of direct benefit, or yields vitally importan...
March 22, 2013
[FierceBiotech | By John Carroll] PRACS Institute, the CRO that attempted to rise Phoenix-like from the ashes of scandal-plagued Cetero Research, has reportedly slammed its doors shut, laying off hundreds of workers with virtually no notice and l...
February 28, 2013
[The Atlantic] For people struggling to put food on the table and a roof over their heads, “voluntary” participation in clinical trials is a slippery slope. While disclosure of new data from pharmaceutical companies is a good first step, qu...
November 22, 2012
A team led by our friend and colleague Charles Weijer at the University of Western Ontario has just issued guideliens for what are known as “cluster randomized trials” (CRTs). See the story here: Western-led team delivers world-first ethics guidelines. CRTs are clinical trials in which randomization occurs across groups of participants, or across institutions, rather […]
November 12, 2012
Generally, when westerners think of people in foreign lands participating as human subjects in clinical trials, we think of the developing world. That image is somewhat incomplete. This was from September, but well worth a look at this NYT piece if you missed it: Russians Eagerly Participate in Medical Experiments, Despite Risks As a test […]
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August 14, 2013 6:27 pm
Licensed drugs have to go through rigorous trials. Even if an unlicensed drug works in some way, it might kill you in another way or cause problems.
February 22, 2013 12:41 pm
Parents with children who have rare and debilitating diseases are pushing to change how researchers develop medicines to treat the conditions. The parents want different scientists researching the diseases to share data about the patients so the children won’t need to participate in so many studies.
January 28, 2013 1:33 pm
In real-world practice, women with early-stage breast cancer were more likely to survive if they had a lumpectomy rather than mastectomy, a population-based registry study found.
January 23, 2013 4:32 pm
Experiments with a deadly flu virus, suspended last year after a fierce global debate over safety, will start up again in some laboratories, probably within the next few weeks, scientists say.
December 12, 2012 2:02 pm
Heavy coffee drinkers — those who drink more than four cups a day — may cut their risk of dying from cancers of the mouth and throat by nearly half, according to new research.
December 11, 2012 2:04 pm
The nation’s twin epidemics of obesity and diabetes are robbing more Americans of their sight. The percentage of American adults suffering from uncorrectable vision loss spiked 21% in only about six years, rising to nearly 1.7% of the population.
December 7, 2012 4:33 pm
According to a new study funded by Japanese beer company Sapporo Breweries, a “key ingredient” found in the world’s most popular alcoholic beverage may very well help stave off winter sniffles.
December 5, 2012 7:13 pm
The widely prescribed drug tamoxifen already plays a major role in reducing the risk of death from breast cancer. But a new study suggests that women should be taking the drug for twice as long could upend the standard that has been in place for about 15 years.
November 29, 2012 6:36 pm
The 2010 outbreak of whooping cough (pertussis) in California, which sickened more than 9,000 people and left 10 infants dead, prompted an examination of the current vaccine’s effectiveness. That study concluded that the vaccine is effective but loses power over the years, leaving children 7 to 10 years old particularly susceptible.
November 29, 2012 6:26 pm
The annual number of births per 1,000 women ages 15 to 44 dropped 8% in the U.S. from 2007 to 2010 to 64 births per 1,000, according to a report released Thursday by the nonpartisan Pew center. The U.S. birthrate peaked during the baby boom, at 122.7 in 1957.
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