September 29, 2016 8:00 am
Depression, stress and diet can all alter inflammation. This double-blind, randomized crossover study addressed the impact of daily stressors and a history of major depressive disorder (MDD) on inflammatory responses to high-fat meals. During two separate 9.5 h admissions, 58 healthy women (38 breast cancer survivors and 20 demographically similar controls), mean age 53.1 years, received either a high saturated fat meal or a high oleic sunflower oil meal. The Daily Inventory of Stressful Events assessed prior day stressors and the Structured Clinical Interview for DSM-IV evaluated MDD. As expected, for a woman with no prior day stressors, C-reactive protein (CRP), serum amyloid A (SAA), intercellular adhesion molecule-1 (sICAM-1) and vascular cell adhesion molecule-1 (sVCAM-1) were higher following the saturated fat meal than the high oleic sunflower oil meal after controlling for pre-meal measures, age, trunk fat and physical activity. But if a woman had prior day stressors, these meal-related differences disappeared—because the stressors heightened CRP, SAA, sICAM-1 and sVCAM-1 responses to the sunflower oil meal, making it look more like the responses to the saturated fat meal. In addition, women with an MDD history had higher post-meal blood pressure responses than those without a similar history. These data show how recent stressors and an MDD history can reverberate through metabolic alterations, promoting inflammatory and atherogenic responses.
September 28, 2016 10:50 am
The world’s first baby to be born from a new procedure that combines the DNA of three people appears to be healthy, according to doctors in the US who oversaw the treatment.
September 23, 2016 8:00 am
The woman on the other end of the phone spoke lightheartedly of spring and of her 81st birthday the previous week. “Who did you celebrate with, Beryl?” asked Alison, whose job was to offer a kind ear. “No one, I…” And with that, Beryl’s cheer turned to despair.
September 22, 2016 8:00 am
A terminally ill 17-year-old has become the first minor to be helped to die in Belgium since age restrictions on euthanasia requests were removed two years ago, officials say.
September 20, 2016 8:00 am
The first of three planned presidential debates will take place at Hofstra University in Hempstead, N.Y., on Sept. 26. Maybe it’s good the debate is slated for a gym. If Hillary Clinton and Donald Trump are really serious about proving their physical vigor and stamina, they can do laps in the arena while they answer questions.
September 16, 2016 8:00 am
High deductible health plans are the new normal. Just over half of employees this year have a health insurance policy with a deductible of at least $1,000, according to a survey of employers from the Kaiser Family Foundation.
September 13, 2016 8:00 am
Hillary Clinton’s begrudging release of information related to her health on Sunday follows a pattern set by candidates and many who have won the Oval Office. It is a pattern of secrecy and, in some cases, cover-ups that would be scandalous if they occurred on other issues of policy.
September 1, 2016 8:00 am
It’s another sign that an era of untreatable bacterial infections is inching closer. Today, the World Health Organization (WHO) released new guidelines for treating gonorrhea that reflect the sobering reality that this sexually transmitted disease is becoming ever more difficult to treat. WHO recommends no longer using quinolones, a class of antibiotics that has become less and less effective. And for the first time, the agency makes suggestions on what to do when none of the standard drugs work.
September 1, 2016 8:00 am
Ohio’s restrictions on the so-called abortion pill led to a higher rate of side effects, more doctor visits and additional medical treatment for patients, according to a new study.
August 25, 2016 8:00 am
Hundreds of pharmaceutical and medical device companies continue to pay doctors as promotional speakers and advisers after they’ve been disciplined for serious misconduct, according to an analysis by ProPublica.